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Photoparoxysmal response and its characteristics in a large EEG database using the SCORE system

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Photoparoxysmal response and its characteristics in a large EEG database using the SCORE system. / Meritam Larsen, Pirgit; Wüstenhagen, Stephan; Terney, Daniella; Gardella, Elena; Alving, Jørgen; Aurlien, Harald; Beniczky, Sándor.

In: Clinical Neurophysiology, Vol. 132, No. 2, 02.2021, p. 365-371.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Meritam Larsen, P, Wüstenhagen, S, Terney, D, Gardella, E, Alving, J, Aurlien, H & Beniczky, S 2021, 'Photoparoxysmal response and its characteristics in a large EEG database using the SCORE system', Clinical Neurophysiology, vol. 132, no. 2, pp. 365-371. https://doi.org/10.1016/j.clinph.2020.10.029

APA

Meritam Larsen, P., Wüstenhagen, S., Terney, D., Gardella, E., Alving, J., Aurlien, H., & Beniczky, S. (2021). Photoparoxysmal response and its characteristics in a large EEG database using the SCORE system. Clinical Neurophysiology, 132(2), 365-371. https://doi.org/10.1016/j.clinph.2020.10.029

CBE

Meritam Larsen P, Wüstenhagen S, Terney D, Gardella E, Alving J, Aurlien H, Beniczky S. 2021. Photoparoxysmal response and its characteristics in a large EEG database using the SCORE system. Clinical Neurophysiology. 132(2):365-371. https://doi.org/10.1016/j.clinph.2020.10.029

MLA

Vancouver

Meritam Larsen P, Wüstenhagen S, Terney D, Gardella E, Alving J, Aurlien H et al. Photoparoxysmal response and its characteristics in a large EEG database using the SCORE system. Clinical Neurophysiology. 2021 Feb;132(2):365-371. https://doi.org/10.1016/j.clinph.2020.10.029

Author

Meritam Larsen, Pirgit ; Wüstenhagen, Stephan ; Terney, Daniella ; Gardella, Elena ; Alving, Jørgen ; Aurlien, Harald ; Beniczky, Sándor. / Photoparoxysmal response and its characteristics in a large EEG database using the SCORE system. In: Clinical Neurophysiology. 2021 ; Vol. 132, No. 2. pp. 365-371.

Bibtex

@article{37221a6e22f54c66be10a07705ebea5b,
title = "Photoparoxysmal response and its characteristics in a large EEG database using the SCORE system",
abstract = "Objective: To characterize photoparoxysmal EEG response (PPR) using a standardized protocol of intermittent photic stimulation (IPS) and standardized definitions for PPR, classified into six types. Methods: Using the SCORE system (Standardized Computer-Based Organized Reporting of EEG) we prospectively built a large database of standardized EEG annotations. In this study, we extracted the features related to PPR from the structured dataset consisting of 10,671 EEG recordings with IPS, from 7,188 patients. Results: The standardized IPS protocol elicited PPR in 375 recordings (3.5%), in 288 patients (4%), with a preponderance among young (11–20 years) and female patients (67%). PPR was persistent in patients with multiple recordings. The most frequent type of PPR was activation of preexisting epileptogenic area (58%), followed by generalized-PPR limited to the stimulus train (22%). We could not find any recording with self-sustained posterior response. Seizures were elicited in 27% of patients with PPR, most often myoclonic seizures and absences, in patients with self-sustained generalized PPR. Conclusions: The most common type of PPR was accentuation of preexisting epileptogenic area. Self-sustained posterior response could not be documented. Self-sustained generalized-PPR had the highest association with seizures. Significance: Using standardized stimulation protocol and definitions for PPR types, IPS provides high diagnostic yield.",
keywords = "Classification, EEG, Epilepsy, Intermittent photic stimulation, Photoparoxysmal response, Photosensitivity",
author = "{Meritam Larsen}, Pirgit and Stephan W{\"u}stenhagen and Daniella Terney and Elena Gardella and J{\o}rgen Alving and Harald Aurlien and S{\'a}ndor Beniczky",
note = "Funding Information: We express our gratitude to Rune Dybdahl for the Information-Technology support. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Publisher Copyright: {\textcopyright} 2020 International Federation of Clinical Neurophysiology Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2021",
month = feb,
doi = "10.1016/j.clinph.2020.10.029",
language = "English",
volume = "132",
pages = "365--371",
journal = "Clinical Neurophysiology",
issn = "1388-2457",
publisher = "Elsevier Ireland Ltd.",
number = "2",

}

RIS

TY - JOUR

T1 - Photoparoxysmal response and its characteristics in a large EEG database using the SCORE system

AU - Meritam Larsen, Pirgit

AU - Wüstenhagen, Stephan

AU - Terney, Daniella

AU - Gardella, Elena

AU - Alving, Jørgen

AU - Aurlien, Harald

AU - Beniczky, Sándor

N1 - Funding Information: We express our gratitude to Rune Dybdahl for the Information-Technology support. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Publisher Copyright: © 2020 International Federation of Clinical Neurophysiology Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2021/2

Y1 - 2021/2

N2 - Objective: To characterize photoparoxysmal EEG response (PPR) using a standardized protocol of intermittent photic stimulation (IPS) and standardized definitions for PPR, classified into six types. Methods: Using the SCORE system (Standardized Computer-Based Organized Reporting of EEG) we prospectively built a large database of standardized EEG annotations. In this study, we extracted the features related to PPR from the structured dataset consisting of 10,671 EEG recordings with IPS, from 7,188 patients. Results: The standardized IPS protocol elicited PPR in 375 recordings (3.5%), in 288 patients (4%), with a preponderance among young (11–20 years) and female patients (67%). PPR was persistent in patients with multiple recordings. The most frequent type of PPR was activation of preexisting epileptogenic area (58%), followed by generalized-PPR limited to the stimulus train (22%). We could not find any recording with self-sustained posterior response. Seizures were elicited in 27% of patients with PPR, most often myoclonic seizures and absences, in patients with self-sustained generalized PPR. Conclusions: The most common type of PPR was accentuation of preexisting epileptogenic area. Self-sustained posterior response could not be documented. Self-sustained generalized-PPR had the highest association with seizures. Significance: Using standardized stimulation protocol and definitions for PPR types, IPS provides high diagnostic yield.

AB - Objective: To characterize photoparoxysmal EEG response (PPR) using a standardized protocol of intermittent photic stimulation (IPS) and standardized definitions for PPR, classified into six types. Methods: Using the SCORE system (Standardized Computer-Based Organized Reporting of EEG) we prospectively built a large database of standardized EEG annotations. In this study, we extracted the features related to PPR from the structured dataset consisting of 10,671 EEG recordings with IPS, from 7,188 patients. Results: The standardized IPS protocol elicited PPR in 375 recordings (3.5%), in 288 patients (4%), with a preponderance among young (11–20 years) and female patients (67%). PPR was persistent in patients with multiple recordings. The most frequent type of PPR was activation of preexisting epileptogenic area (58%), followed by generalized-PPR limited to the stimulus train (22%). We could not find any recording with self-sustained posterior response. Seizures were elicited in 27% of patients with PPR, most often myoclonic seizures and absences, in patients with self-sustained generalized PPR. Conclusions: The most common type of PPR was accentuation of preexisting epileptogenic area. Self-sustained posterior response could not be documented. Self-sustained generalized-PPR had the highest association with seizures. Significance: Using standardized stimulation protocol and definitions for PPR types, IPS provides high diagnostic yield.

KW - Classification

KW - EEG

KW - Epilepsy

KW - Intermittent photic stimulation

KW - Photoparoxysmal response

KW - Photosensitivity

UR - http://www.scopus.com/inward/record.url?scp=85099214214&partnerID=8YFLogxK

U2 - 10.1016/j.clinph.2020.10.029

DO - 10.1016/j.clinph.2020.10.029

M3 - Journal article

C2 - 33450559

AN - SCOPUS:85099214214

VL - 132

SP - 365

EP - 371

JO - Clinical Neurophysiology

JF - Clinical Neurophysiology

SN - 1388-2457

IS - 2

ER -