Persistent Symptoms in Patients Recovering From COVID-19 in Denmark

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Standard

Persistent Symptoms in Patients Recovering From COVID-19 in Denmark. / Leth, Steffen; Gunst, Jesper Damsgaard; Mathiasen, Victor; Hansen, Kristoffer; Søgaard, Ole; Østergaard, Lars; Jensen-Fangel, Søren; Storgaard, Merete; Agergaard, Jane.

In: Open Forum Infectious Diseases, Vol. 8, No. 4, ofab042, 04.2021.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

APA

CBE

MLA

Vancouver

Author

Bibtex

@article{0568baf104524f86a347ffefa2f585bf,
title = "Persistent Symptoms in Patients Recovering From COVID-19 in Denmark",
abstract = "Background: Although persistent symptoms after coronavirus disease 2019 (COVID-19) are emerging as a major complication to the infection, data on the diversity and duration of symptoms are needed.Methods: Patients aged ≥18 years with a positive polymerase chain reaction (PCR) test for severe acute respiratory syndrome coronavirus 2 who were hospitalized at the Department of Infectious Diseases, Aarhus University Hospital, Denmark, in the period from March 11 to May 15 were offered follow-up after hospitalization. On admission, a comprehensive symptom and medical history was collected, including demographic characteristics, duration of symptoms, comorbidities, and concomitant medications. At discharge, patients were offered follow-up consultations-either by telephone or at an in-person visit-at 6 and 12 weeks at our post-COVID-19 outpatient clinic to assess whether symptoms present at admission had resolved.Results: During the inclusion period, 71 patients were admitted with COVID-19. Of these, 10 patients died, 3 were transferred to another region, 4 declined to participate, and 5 were lost to follow-up before the 12-week evaluation. Thus, 49 patients were included. Overall, 96% reported 1 or more persisting symptoms at 12-week follow-up. The main symptoms were fatigue, dyspnea, cough, chemosensory dysfunction, and headache.Conclusions: A wide range of persistent symptoms in patients recovering from COVID-19 were present 12 weeks after hospitalization, calling for larger descriptive studies and interdisciplinary research collaborations.",
author = "Steffen Leth and Gunst, {Jesper Damsgaard} and Victor Mathiasen and Kristoffer Hansen and Ole S{\o}gaard and Lars {\O}stergaard and S{\o}ren Jensen-Fangel and Merete Storgaard and Jane Agergaard",
note = "{\textcopyright} The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.",
year = "2021",
month = apr,
doi = "10.1093/ofid/ofab042",
language = "English",
volume = "8",
journal = "Open Forum Infectious Diseases",
issn = "2328-8957",
publisher = "Oxford University Press",
number = "4",

}

RIS

TY - JOUR

T1 - Persistent Symptoms in Patients Recovering From COVID-19 in Denmark

AU - Leth, Steffen

AU - Gunst, Jesper Damsgaard

AU - Mathiasen, Victor

AU - Hansen, Kristoffer

AU - Søgaard, Ole

AU - Østergaard, Lars

AU - Jensen-Fangel, Søren

AU - Storgaard, Merete

AU - Agergaard, Jane

N1 - © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

PY - 2021/4

Y1 - 2021/4

N2 - Background: Although persistent symptoms after coronavirus disease 2019 (COVID-19) are emerging as a major complication to the infection, data on the diversity and duration of symptoms are needed.Methods: Patients aged ≥18 years with a positive polymerase chain reaction (PCR) test for severe acute respiratory syndrome coronavirus 2 who were hospitalized at the Department of Infectious Diseases, Aarhus University Hospital, Denmark, in the period from March 11 to May 15 were offered follow-up after hospitalization. On admission, a comprehensive symptom and medical history was collected, including demographic characteristics, duration of symptoms, comorbidities, and concomitant medications. At discharge, patients were offered follow-up consultations-either by telephone or at an in-person visit-at 6 and 12 weeks at our post-COVID-19 outpatient clinic to assess whether symptoms present at admission had resolved.Results: During the inclusion period, 71 patients were admitted with COVID-19. Of these, 10 patients died, 3 were transferred to another region, 4 declined to participate, and 5 were lost to follow-up before the 12-week evaluation. Thus, 49 patients were included. Overall, 96% reported 1 or more persisting symptoms at 12-week follow-up. The main symptoms were fatigue, dyspnea, cough, chemosensory dysfunction, and headache.Conclusions: A wide range of persistent symptoms in patients recovering from COVID-19 were present 12 weeks after hospitalization, calling for larger descriptive studies and interdisciplinary research collaborations.

AB - Background: Although persistent symptoms after coronavirus disease 2019 (COVID-19) are emerging as a major complication to the infection, data on the diversity and duration of symptoms are needed.Methods: Patients aged ≥18 years with a positive polymerase chain reaction (PCR) test for severe acute respiratory syndrome coronavirus 2 who were hospitalized at the Department of Infectious Diseases, Aarhus University Hospital, Denmark, in the period from March 11 to May 15 were offered follow-up after hospitalization. On admission, a comprehensive symptom and medical history was collected, including demographic characteristics, duration of symptoms, comorbidities, and concomitant medications. At discharge, patients were offered follow-up consultations-either by telephone or at an in-person visit-at 6 and 12 weeks at our post-COVID-19 outpatient clinic to assess whether symptoms present at admission had resolved.Results: During the inclusion period, 71 patients were admitted with COVID-19. Of these, 10 patients died, 3 were transferred to another region, 4 declined to participate, and 5 were lost to follow-up before the 12-week evaluation. Thus, 49 patients were included. Overall, 96% reported 1 or more persisting symptoms at 12-week follow-up. The main symptoms were fatigue, dyspnea, cough, chemosensory dysfunction, and headache.Conclusions: A wide range of persistent symptoms in patients recovering from COVID-19 were present 12 weeks after hospitalization, calling for larger descriptive studies and interdisciplinary research collaborations.

U2 - 10.1093/ofid/ofab042

DO - 10.1093/ofid/ofab042

M3 - Journal article

C2 - 33875970

VL - 8

JO - Open Forum Infectious Diseases

JF - Open Forum Infectious Diseases

SN - 2328-8957

IS - 4

M1 - ofab042

ER -