Pediatric cleft palate patients show a 3- to 5-fold increase in cumulative radiation exposure from dental radiology compared with an age- and gender-matched population: a retrospective cohort study

Reinhilde Jacobs; Ruben Pauwels; William C. Scarfe; Carl De Cock; Karl Dula; Guy Willems; An Verdonck; Constantinus Politis

doi:10.1007/s00784-017-2274-0

Pediatric cleft palate patients show a 3- to 5-fold increase in cumulative radiation exposure from dental radiology compared with an age- and gender-matched population: a retrospective cohort study

Reinhilde Jacobs^*, Ruben Pauwels, William C. Scarfe, Carl De Cock, Karl Dula, Guy Willems, An Verdonck, Constantinus Politis

^*Corresponding author for this work

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

24 Citations (Scopus)

Abstract

Objective: The objective of the study was to compare estimates of pediatric cumulative exposure and lifetime attributable risk (LAR) of radiation-induced cancer from dental radiology between cleft palate (CP) subjects and age- and gender-matched controls (non-CP), with and without orthodontic treatment. Materials and methods: The radiation exposure frequency of CP subjects and non-CP controls with and without orthodontic treatment was compared for two-dimensional radiography (intra-oral, panoramic and cephalometric radiography), computed tomography (CT), and cone-beam CT (CBCT) using cumulative radiation dose as an estimate. From this dose estimate, the age- and gender-dependent risk for radiation-induced stochastic effects was calculated for each patient group. Results: CP patients received more radiographic examinations than non-CP controls, with the exception of intra-oral radiographs. The cumulative dose to CP patients was considerably higher (1963 μSv at the age of 20 years) than non-CP patients with (597 μSv) and without (383 μSv) orthodontic treatment, primarily due to the higher frequency of CT scanning. Accordingly, CP patients had a three to five times higher LAR than non-CP patients. Conclusions: This study suggests a significantly higher lifetime radiation exposure to CP patients than non-CP controls from dental radiographic procedures. Diagnostic benefits from the use of CT and CBCT in children must be justified and appropriate dose optimization strategies implemented. Clinical relevance: The present study indicates the need for proper justification and optimization of pediatric exposures in dentistry, with a special focus on high-risk groups.

Original language	English
Journal	Clinical Oral Investigations
Volume	22
Issue	4
Pages (from-to)	1783-1793
Number of pages	11
ISSN	1432-6981
DOIs	https://doi.org/10.1007/s00784-017-2274-0
Publication status	Published - 1 May 2018
Externally published	Yes

Keywords

Cleft palate
Pediatric dentistry
Radiation dosimetry
Radiation protection
Radiation-induced cancer

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10.1007/s00784-017-2274-0

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Jacobs, R., Pauwels, R., Scarfe, W. C., De Cock, C., Dula, K., Willems, G., Verdonck, A., & Politis, C. (2018). Pediatric cleft palate patients show a 3- to 5-fold increase in cumulative radiation exposure from dental radiology compared with an age- and gender-matched population: a retrospective cohort study. Clinical Oral Investigations, 22(4), 1783-1793. https://doi.org/10.1007/s00784-017-2274-0

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title = "Pediatric cleft palate patients show a 3- to 5-fold increase in cumulative radiation exposure from dental radiology compared with an age- and gender-matched population: a retrospective cohort study",

abstract = "Objective: The objective of the study was to compare estimates of pediatric cumulative exposure and lifetime attributable risk (LAR) of radiation-induced cancer from dental radiology between cleft palate (CP) subjects and age- and gender-matched controls (non-CP), with and without orthodontic treatment. Materials and methods: The radiation exposure frequency of CP subjects and non-CP controls with and without orthodontic treatment was compared for two-dimensional radiography (intra-oral, panoramic and cephalometric radiography), computed tomography (CT), and cone-beam CT (CBCT) using cumulative radiation dose as an estimate. From this dose estimate, the age- and gender-dependent risk for radiation-induced stochastic effects was calculated for each patient group. Results: CP patients received more radiographic examinations than non-CP controls, with the exception of intra-oral radiographs. The cumulative dose to CP patients was considerably higher (1963 μSv at the age of 20 years) than non-CP patients with (597 μSv) and without (383 μSv) orthodontic treatment, primarily due to the higher frequency of CT scanning. Accordingly, CP patients had a three to five times higher LAR than non-CP patients. Conclusions: This study suggests a significantly higher lifetime radiation exposure to CP patients than non-CP controls from dental radiographic procedures. Diagnostic benefits from the use of CT and CBCT in children must be justified and appropriate dose optimization strategies implemented. Clinical relevance: The present study indicates the need for proper justification and optimization of pediatric exposures in dentistry, with a special focus on high-risk groups.",

keywords = "Cleft palate, Pediatric dentistry, Radiation dosimetry, Radiation protection, Radiation-induced cancer",

author = "Reinhilde Jacobs and Ruben Pauwels and Scarfe, {William C.} and {De Cock}, Carl and Karl Dula and Guy Willems and An Verdonck and Constantinus Politis",

note = "Publisher Copyright: {\textcopyright} 2017, Springer-Verlag GmbH Germany, part of Springer Nature.",

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Jacobs, R, Pauwels, R, Scarfe, WC, De Cock, C, Dula, K, Willems, G, Verdonck, A & Politis, C 2018, 'Pediatric cleft palate patients show a 3- to 5-fold increase in cumulative radiation exposure from dental radiology compared with an age- and gender-matched population: a retrospective cohort study', Clinical Oral Investigations, vol. 22, no. 4, pp. 1783-1793. https://doi.org/10.1007/s00784-017-2274-0

Pediatric cleft palate patients show a 3- to 5-fold increase in cumulative radiation exposure from dental radiology compared with an age- and gender-matched population: a retrospective cohort study. / Jacobs, Reinhilde; Pauwels, Ruben; Scarfe, William C. et al.
In: Clinical Oral Investigations, Vol. 22, No. 4, 01.05.2018, p. 1783-1793.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

TY - JOUR

T1 - Pediatric cleft palate patients show a 3- to 5-fold increase in cumulative radiation exposure from dental radiology compared with an age- and gender-matched population

T2 - a retrospective cohort study

AU - Jacobs, Reinhilde

AU - Pauwels, Ruben

AU - Scarfe, William C.

AU - De Cock, Carl

AU - Dula, Karl

AU - Willems, Guy

AU - Verdonck, An

AU - Politis, Constantinus

PY - 2018/5/1

Y1 - 2018/5/1

N2 - Objective: The objective of the study was to compare estimates of pediatric cumulative exposure and lifetime attributable risk (LAR) of radiation-induced cancer from dental radiology between cleft palate (CP) subjects and age- and gender-matched controls (non-CP), with and without orthodontic treatment. Materials and methods: The radiation exposure frequency of CP subjects and non-CP controls with and without orthodontic treatment was compared for two-dimensional radiography (intra-oral, panoramic and cephalometric radiography), computed tomography (CT), and cone-beam CT (CBCT) using cumulative radiation dose as an estimate. From this dose estimate, the age- and gender-dependent risk for radiation-induced stochastic effects was calculated for each patient group. Results: CP patients received more radiographic examinations than non-CP controls, with the exception of intra-oral radiographs. The cumulative dose to CP patients was considerably higher (1963 μSv at the age of 20 years) than non-CP patients with (597 μSv) and without (383 μSv) orthodontic treatment, primarily due to the higher frequency of CT scanning. Accordingly, CP patients had a three to five times higher LAR than non-CP patients. Conclusions: This study suggests a significantly higher lifetime radiation exposure to CP patients than non-CP controls from dental radiographic procedures. Diagnostic benefits from the use of CT and CBCT in children must be justified and appropriate dose optimization strategies implemented. Clinical relevance: The present study indicates the need for proper justification and optimization of pediatric exposures in dentistry, with a special focus on high-risk groups.

AB - Objective: The objective of the study was to compare estimates of pediatric cumulative exposure and lifetime attributable risk (LAR) of radiation-induced cancer from dental radiology between cleft palate (CP) subjects and age- and gender-matched controls (non-CP), with and without orthodontic treatment. Materials and methods: The radiation exposure frequency of CP subjects and non-CP controls with and without orthodontic treatment was compared for two-dimensional radiography (intra-oral, panoramic and cephalometric radiography), computed tomography (CT), and cone-beam CT (CBCT) using cumulative radiation dose as an estimate. From this dose estimate, the age- and gender-dependent risk for radiation-induced stochastic effects was calculated for each patient group. Results: CP patients received more radiographic examinations than non-CP controls, with the exception of intra-oral radiographs. The cumulative dose to CP patients was considerably higher (1963 μSv at the age of 20 years) than non-CP patients with (597 μSv) and without (383 μSv) orthodontic treatment, primarily due to the higher frequency of CT scanning. Accordingly, CP patients had a three to five times higher LAR than non-CP patients. Conclusions: This study suggests a significantly higher lifetime radiation exposure to CP patients than non-CP controls from dental radiographic procedures. Diagnostic benefits from the use of CT and CBCT in children must be justified and appropriate dose optimization strategies implemented. Clinical relevance: The present study indicates the need for proper justification and optimization of pediatric exposures in dentistry, with a special focus on high-risk groups.

KW - Cleft palate

KW - Pediatric dentistry

KW - Radiation dosimetry

KW - Radiation protection

KW - Radiation-induced cancer

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DO - 10.1007/s00784-017-2274-0

M3 - Journal article

C2 - 29188451

AN - SCOPUS:85035331598

SN - 1432-6981

VL - 22

SP - 1783

EP - 1793

JO - Clinical Oral Investigations

JF - Clinical Oral Investigations

IS - 4

ER -

Pediatric cleft palate patients show a 3- to 5-fold increase in cumulative radiation exposure from dental radiology compared with an age- and gender-matched population: a retrospective cohort study

Abstract

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