Partial oral treatment of endocarditis

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  • Kasper Iversen, Department of Cardiology, Rigshospitalet, Copenhagen, Denmark
  • ,
  • Nis Baun Høst, Department of Cardiology, Bispebjerg Hospital, Copenhagen, Denmark, Denmark
  • Niels Eske Bruun, Department of Cardiology, Gentofte Hospital, Copenhagen, Denmark, Denmark
  • Hanne Elming, Department of Cardiology, Roskilde Hospital, Roskilde, Denmark
  • ,
  • Bettina Pump, Department of Cardiology, Roskilde Hospital, Roskilde, Denmark
  • ,
  • Jens Jørgen Christensen, Department of Microbiology, Slagelse Hospital, Slagelse, Denmark, Denmark
  • Sabine Gill, Department of Cardiology, Odense University Hospital, Odense, Denmark., Denmark
  • Flemming Schønning Rosenvinge, Department of Microbiology, Odense University Hospital, Odense, Denmark, Denmark
  • Henrik Wiggers
  • Kurt Fuursted, Denmark
  • Claus Holst-Hansen
  • Eva Korup, Aalborg University Hospital, Aalborg, Denmark., Denmark
  • Henrik Carl Schønheyder
  • Christian Hassager, Department of Cardiology, Rigshospitalet, Copenhagen, Denmark
  • Dan Eik Høfsten, Department of Cardiology, Rigshospitalet, Copenhagen, Denmark
  • Jannik Helweg Larsen, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
  • ,
  • Claus Ernst Moser, Department of Microbiology, Rigshospitalet, Copenhagen, Denmark, Denmark
  • Nikolaj Ihlemann, Department of Cardiology, Rigshospitalet, Copenhagen, Denmark, Denmark
  • Henning Bundgaard, Department of Cardiology, Rigshospitalet, Copenhagen, Denmark
Guidelines for the treatment of left-sided infective endocarditis (IE) recommend 4 to 6 weeks of intravenous antibiotics. Conversion from intravenous to oral antibiotics in clinically stabilized patients could reduce the side effects associated with intravenous treatment and shorten the length of hospital stay. Evidence supporting partial oral therapy as an alternative to the routinely recommended continued parenteral therapy is scarce, although observational data suggest that this strategy may be safe and effective.
Original languageEnglish
JournalAmerican Heart Journal
Volume165
Issue2
Pages (from-to)116-22
Number of pages7
ISSN0002-8703
DOIs
Publication statusPublished - 2013

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