Osteopontin reduces biofilm formation in a multi-species model of dental biofilm

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Bacteria in dental biofilms produce organic acids upon exposure to fermentable dietary carbohydrates. Repeated pH drops at the biofilmtooth interface lead to slow demineralization of the dental hard tissues and the development of carious lesions. The most common and most effective means of caries prevention is the mechanical removal of dental biofilm. However, self-performed mechanical cleaning using both tooth brush and interdental floss does not result in full removal of the biofilm [1]-[3], and combating the high world-wide prevalence of caries is still one of the major challenges for dental research [4].

Original languageEnglish
Title of host publicationBiofilm Control and Antimicrobial Agents
Number of pages14
PublisherApple Academic Press
Publication year1 Jan 2014
ISBN (print)9781771880022
ISBN (Electronic)9781482239492
Publication statusPublished - 1 Jan 2014

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