Abstract
Objectives
Obsessive-Compulsive Disorder (OCD) affects 1-2% of the child and adolescent population, severely affecting their quality of life. Cognitive-behavioral therapy (CBT) and medication are efficacious, but a significant proportion of patients still fail to respond adequately to treatment. Few studies have systematically looked at the long-term outcomes, specific group outcome trajectories, and predictors of outcomes. The overall aim is to use the study results to guide practitioners with patients who do not respond to CBT.
Methods
Six presentations are based on results from the Nordic Long-term OCD Treatment Study (NordLOTS) that included 269 OCD patients aged 7-17 years from Denmark, Norway and Sweden. All participants received stepped-care treatment starting with 14 weekly sessions of CBT. Non-responders were randomized to either prolonged CBT or SSRIs. All patients were monitored for three years after ended CBT.
Results
Long-term treatment effects for pediatric OCD were sustainable for the sample as a whole, but subgroups with less favorable outcome trajectories were identified based on both OCD severity and functional impairment. Relapse at some point during follow-up was not uncommon. Predictors of different outcomes are identified.
Conclusions
Outcome data from the NordLOTS will be discussed with focus on long-term treatment outcomes, including different groups of outcome trajectories based on OCD type and severity, functional impairment and comorbidity. Various predictors of treatment outcomes will be discussed, including comorbidity and OCD symptom types. Findings will be presented and discussed in relation to their importance for clinical practice, including key issues that remain in the treatment of OCD.
Obsessive-Compulsive Disorder (OCD) affects 1-2% of the child and adolescent population, severely affecting their quality of life. Cognitive-behavioral therapy (CBT) and medication are efficacious, but a significant proportion of patients still fail to respond adequately to treatment. Few studies have systematically looked at the long-term outcomes, specific group outcome trajectories, and predictors of outcomes. The overall aim is to use the study results to guide practitioners with patients who do not respond to CBT.
Methods
Six presentations are based on results from the Nordic Long-term OCD Treatment Study (NordLOTS) that included 269 OCD patients aged 7-17 years from Denmark, Norway and Sweden. All participants received stepped-care treatment starting with 14 weekly sessions of CBT. Non-responders were randomized to either prolonged CBT or SSRIs. All patients were monitored for three years after ended CBT.
Results
Long-term treatment effects for pediatric OCD were sustainable for the sample as a whole, but subgroups with less favorable outcome trajectories were identified based on both OCD severity and functional impairment. Relapse at some point during follow-up was not uncommon. Predictors of different outcomes are identified.
Conclusions
Outcome data from the NordLOTS will be discussed with focus on long-term treatment outcomes, including different groups of outcome trajectories based on OCD type and severity, functional impairment and comorbidity. Various predictors of treatment outcomes will be discussed, including comorbidity and OCD symptom types. Findings will be presented and discussed in relation to their importance for clinical practice, including key issues that remain in the treatment of OCD.
| Original language | English |
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| Publication date | 1 Jul 2023 |
| Publication status | Published - 1 Jul 2023 |
| Event | 20th International Congress of the European Society for Child and Adolescent Psychiatry - Copenhagen, Denmark Duration: 29 Jun 2023 → 1 Jul 2023 Conference number: 20 https://www.escap2023.eu/ |
Conference
| Conference | 20th International Congress of the European Society for Child and Adolescent Psychiatry |
|---|---|
| Number | 20 |
| Country/Territory | Denmark |
| City | Copenhagen |
| Period | 29/06/2023 → 01/07/2023 |
| Internet address |