Observation of molecular inhibition and binding structures of amyloid peptides

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Unveiling interactions between labeling molecules and amyloid fibrils is essential to develop new detection methods for studying amyloid structures under various conditions. This review endeavours to reflect the progress in studying interactions between molecular inhibitors and amyloid peptides using a series of experimental approaches, such as X-ray diffraction, nuclear magnetic resonance, scanning probe microscopy, and electron microscopy. The revealed binding mechanisms of anti-amyloid drugs and target proteins could benefit the rational design of drugs for prevention or treatment of amyloidal diseases.
Original languageEnglish
Pages (from-to)1895-909
Number of pages15
Publication statusPublished - 2012

    Research areas

  • Amyloidogenic Proteins, Binding Sites, Models, Chemical, Protein Binding

See relations at Aarhus University Citationformats

ID: 48794980