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Nucleic Acids and Enzymes at Electrodes: Electrochemical Nanomedical Biosensors and Biofuel Cell Development

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Starting from the development of the first electrochemical biosensor for glucose, as far as in 1962, the electrochemical biosensor research area underwent a dramatic evolution both in scientific and commercial directions. At present, electrochemical biosensors are widely used in medical practice, by offering extremely sensitive and accurate yet simple, rapid, and inexpensive biosensing platforms (1). In this talk, I will discuss the developed at iNANO reagentless enzymatic biosensors, in which the enzyme is directly electronically coupled to the electrode (1-3), and advanced genosensor platforms for nanomedicine, based on DNA and RNA architectures (1, 4, 5), in which binding of the analyte results in the electrochemically translatable conformational nanoswitching of nucleic acids, with a special emphasis on electronic molecular beacon systems for genetic and small-molecule electroanalysis. Future perspectives of the biosensor research and such biotechnological applications as enzyme electrodes for sustainable energy production (6) will be discussed.
Original languageEnglish
Publication year2011
Number of pages1
Publication statusPublished - 2011
EventAcademic Forum on Nanochemistry 2011 - Chongqing, China
Duration: 20 Jun 2011 → …


ConferenceAcademic Forum on Nanochemistry 2011
Period20/06/2011 → …

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