Noninvasive Stimulation of the Human Brain: Activation of Multiple Cortical Circuits

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Noninvasive Stimulation of the Human Brain : Activation of Multiple Cortical Circuits. / Di Lazzaro, Vincenzo; Rothwell, John; Capogna, Marco.

In: Neuroscientist, Vol. 24, No. 3, 06.2018, p. 246-260.

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Di Lazzaro, Vincenzo ; Rothwell, John ; Capogna, Marco. / Noninvasive Stimulation of the Human Brain : Activation of Multiple Cortical Circuits. In: Neuroscientist. 2018 ; Vol. 24, No. 3. pp. 246-260.

Bibtex

@article{9016c5df7d624c5f9b13cc33c59b8601,
title = "Noninvasive Stimulation of the Human Brain: Activation of Multiple Cortical Circuits",
abstract = "Noninvasive brain stimulation methods, such as transcranial electric stimulation and transcranial magnetic stimulation are widely used tools for both basic research and clinical applications. However, the cortical circuits underlying their effects are poorly defined. Here we review the current knowledge based on data mostly coming from experiments performed on human subjects, and also to a lesser extent on rodent or primate models. The data suggest that multiple mechanisms are likely to be involved, such as the direct activation of layer V pyramidal neurons, but also of different types of GABAergic interneurons. In this regard, we propose a key role for a specific type of interneuron known as neurogliaform cell.",
keywords = "Journal Article, neurogliaform cell, transcranial electrical stimulation, cortical pyramidal neuron, transcranial magnetic stimulation, cortical interneuron, Neurons/physiology, Humans, Brain/physiology, Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation, Animals, Neural Pathways/physiology",
author = "{Di Lazzaro}, Vincenzo and John Rothwell and Marco Capogna",
year = "2018",
month = jun,
doi = "10.1177/1073858417717660",
language = "English",
volume = "24",
pages = "246--260",
journal = "Neuroscientist",
issn = "1073-8584",
publisher = "Sage Publications, Inc.",
number = "3",

}

RIS

TY - JOUR

T1 - Noninvasive Stimulation of the Human Brain

T2 - Activation of Multiple Cortical Circuits

AU - Di Lazzaro, Vincenzo

AU - Rothwell, John

AU - Capogna, Marco

PY - 2018/6

Y1 - 2018/6

N2 - Noninvasive brain stimulation methods, such as transcranial electric stimulation and transcranial magnetic stimulation are widely used tools for both basic research and clinical applications. However, the cortical circuits underlying their effects are poorly defined. Here we review the current knowledge based on data mostly coming from experiments performed on human subjects, and also to a lesser extent on rodent or primate models. The data suggest that multiple mechanisms are likely to be involved, such as the direct activation of layer V pyramidal neurons, but also of different types of GABAergic interneurons. In this regard, we propose a key role for a specific type of interneuron known as neurogliaform cell.

AB - Noninvasive brain stimulation methods, such as transcranial electric stimulation and transcranial magnetic stimulation are widely used tools for both basic research and clinical applications. However, the cortical circuits underlying their effects are poorly defined. Here we review the current knowledge based on data mostly coming from experiments performed on human subjects, and also to a lesser extent on rodent or primate models. The data suggest that multiple mechanisms are likely to be involved, such as the direct activation of layer V pyramidal neurons, but also of different types of GABAergic interneurons. In this regard, we propose a key role for a specific type of interneuron known as neurogliaform cell.

KW - Journal Article

KW - neurogliaform cell

KW - transcranial electrical stimulation

KW - cortical pyramidal neuron

KW - transcranial magnetic stimulation

KW - cortical interneuron

KW - Neurons/physiology

KW - Humans

KW - Brain/physiology

KW - Transcranial Magnetic Stimulation

KW - Transcranial Direct Current Stimulation

KW - Animals

KW - Neural Pathways/physiology

U2 - 10.1177/1073858417717660

DO - 10.1177/1073858417717660

M3 - Review

C2 - 28659070

VL - 24

SP - 246

EP - 260

JO - Neuroscientist

JF - Neuroscientist

SN - 1073-8584

IS - 3

ER -