No decrease in perseverance and performance on cognitive tasks in Danish cohort of hormonal contraceptive users

Maria Nissen Byg, Andrea Dioni, Michael Winterdahl

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

3 Citations (Scopus)

Abstract

Cognitive consequences of hormonal contraceptives (HCs) are largely underexplored, despite the popularity of use. This study investigates the association between perseverance during cognitively challenging tasks and the use of HCs among Danish women. We hypothesised that women using HCs show decreased perseverance across tasks compared to their naturally cycling counterparts. We further hypothesised that HC using women would show decreased performance as a measure of accuracy (i.e. more incorrect answers) compared to naturally cycling women. The study used a cross-sectional repeated measures design, consisting of a Danish version of the Anagram Persistence Task and the Hagen Matrices Test, followed by an extensive survey documenting menstrual and HC history for each participant. The study was conducted online. Data processing was conducted on data from 129 participants. The former hypothesis was analysed through multilevel regression with a nested random effects structure on log-transformed data. The latter hypothesis was analysed through a multilevel generalised linear model with a nested random effects structure using the binomial family. No support was found for either of the hypotheses.

Original languageEnglish
JournalActa Neuropsychiatrica
Volume35
Issue4
Pages (from-to)1-6
Number of pages6
ISSN0924-2708
DOIs
Publication statusPublished - Aug 2023

Keywords

  • Anagram Persistence Task
  • Hagen Matrices Test
  • Hormonal contraception
  • Oral Contraceptives
  • Perseverance
  • Contraceptives, Oral, Hormonal/adverse effects
  • Cross-Sectional Studies
  • Humans
  • Denmark
  • Female
  • Surveys and Questionnaires
  • Cognition

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