No additional copies of HERV-Fc1 in the germ line of multiple sclerosis patients

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No additional copies of HERV-Fc1 in the germ line of multiple sclerosis patients. / Nissen, Kari K; Laska, Magdalena Janina; Hansen, Bettina; Pedersen, Finn S; Nexø, Bjørn A.

In: Virology Journal, Vol. 9, No. 188, 08.09.2012, p. 1-4.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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@article{947f752e9b4e4e399b62c646efd8a9bc,
title = "No additional copies of HERV-Fc1 in the germ line of multiple sclerosis patients",
abstract = "Human endogenous retroviruses (HERVs) are suspected to play a role in the development of multiple sclerosis (MS). This suspicion has in part been based on increased expression of viral RNA or proteins or antibodies targeting retroviral products in MS patients. Recently, our group provided genetic evidence for association between the endogenous retrovirus HERV-Fc1 and MS, suggesting that HERV-Fc1 plays a role in this multifactorial disease. We have found increased expression of HERV-Fc1 in MS patients suffering from recent attack, but the underlying mechanism for association is still unknown.",
author = "Nissen, {Kari K} and Laska, {Magdalena Janina} and Bettina Hansen and Pedersen, {Finn S} and Nex{\o}, {Bj{\o}rn A}",
year = "2012",
month = sep,
day = "8",
doi = "10.1186/1743-422X-9-188",
language = "English",
volume = "9",
pages = "1--4",
journal = "Virology Journal",
issn = "1743-422X",
publisher = "BioMed Central",
number = "188",

}

RIS

TY - JOUR

T1 - No additional copies of HERV-Fc1 in the germ line of multiple sclerosis patients

AU - Nissen, Kari K

AU - Laska, Magdalena Janina

AU - Hansen, Bettina

AU - Pedersen, Finn S

AU - Nexø, Bjørn A

PY - 2012/9/8

Y1 - 2012/9/8

N2 - Human endogenous retroviruses (HERVs) are suspected to play a role in the development of multiple sclerosis (MS). This suspicion has in part been based on increased expression of viral RNA or proteins or antibodies targeting retroviral products in MS patients. Recently, our group provided genetic evidence for association between the endogenous retrovirus HERV-Fc1 and MS, suggesting that HERV-Fc1 plays a role in this multifactorial disease. We have found increased expression of HERV-Fc1 in MS patients suffering from recent attack, but the underlying mechanism for association is still unknown.

AB - Human endogenous retroviruses (HERVs) are suspected to play a role in the development of multiple sclerosis (MS). This suspicion has in part been based on increased expression of viral RNA or proteins or antibodies targeting retroviral products in MS patients. Recently, our group provided genetic evidence for association between the endogenous retrovirus HERV-Fc1 and MS, suggesting that HERV-Fc1 plays a role in this multifactorial disease. We have found increased expression of HERV-Fc1 in MS patients suffering from recent attack, but the underlying mechanism for association is still unknown.

U2 - 10.1186/1743-422X-9-188

DO - 10.1186/1743-422X-9-188

M3 - Journal article

C2 - 22958517

VL - 9

SP - 1

EP - 4

JO - Virology Journal

JF - Virology Journal

SN - 1743-422X

IS - 188

ER -