[N-methyl-11C]Mirtazapine for positron emission tomography neuroimaging of antidepressant actions in humans

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • Katalin Marthi
  • ,
  • Steen Jakobsen
  • Dirk Bender
  • Søren B Hansen
  • ,
  • Stefan Bo Smith
  • ,
  • Flemming Hermansen, Denmark
  • Raben Rosenberg, Denmark
  • Donald F Smith, Denmark
Many actions of antidepressant drugs cannot yet be studied using positron emission tomography (PET) neuroimaging due to lack of suitable radioligands. We believe that mirtazapine, radiolabeled with C-11, might be suitable for PET neuroimaging of alpha2-adrenoceptors in selected regions of the living human brain.
Original languageEnglish
JournalPsychopharmacology
Volume174
Issue2
Pages (from-to)260-5
Number of pages6
ISSN0033-3158
DOIs
Publication statusPublished - 2004

    Research areas

  • Adrenergic alpha-Agonists, Antidepressive Agents, Tricyclic, Brain, Humans, Mianserin, Tissue Distribution, Tomography, Emission-Computed

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