ncIDP-assign: a SPARKY extension for the effective NMR assignment of intrinsically disordered proteins

TY - JOUR

T1 - ncIDP-assign

T2 - a SPARKY extension for the effective NMR assignment of intrinsically disordered proteins

AU - Tamiola, Kamil

AU - Mulder, Frans A.A.

PY - 2011

Y1 - 2011

N2 - We describe here the ncIDP-assign extension for the popular NMR assignment program SPARKY, which aids in the sequence-specific resonance assignment of intrinsically disordered proteins (IDPs). The assignment plugin greatly facilitates the effective matching of a set of connected resonances to the correct position in the sequence by making use of IDP random coil chemical shifts. AVAILABILITY: The ncIDP-assign extension is available at http://www.protein-nmr.org/.

AB - We describe here the ncIDP-assign extension for the popular NMR assignment program SPARKY, which aids in the sequence-specific resonance assignment of intrinsically disordered proteins (IDPs). The assignment plugin greatly facilitates the effective matching of a set of connected resonances to the correct position in the sequence by making use of IDP random coil chemical shifts. AVAILABILITY: The ncIDP-assign extension is available at http://www.protein-nmr.org/.

KW - Algorithms

KW - Cell Adhesion Molecules, Neuronal

KW - Humans

KW - Magnetic Resonance Imaging

KW - Membrane Proteins

KW - Nerve Tissue Proteins

KW - Nuclear Magnetic Resonance, Biomolecular

KW - Protein Conformation

KW - Software

U2 - 10.1093/bioinformatics/btr054

DO - 10.1093/bioinformatics/btr054

M3 - Journal article

C2 - 21372082

SN - 1367-4811

VL - 27

SP - 1039

EP - 1040

JO - Bioinformatics (Online)

JF - Bioinformatics (Online)

IS - 7

ER -