Nanomaterials and Annelid Immunity:: A Comparative Survey to Reveal the Common Stress and Defense Responses of Two Sentinel Species to Nanomaterials in the Environment

Kornélia Bodó; Nicoló Baranzini; Rossana Girardello; Bohdana Kokhanyuk; Péter Németh; Yuya Hayashi; Annalisa Grimaldi; Péter Engelmann

doi:10.3390/biology9100307

Nanomaterials and Annelid Immunity: A Comparative Survey to Reveal the Common Stress and Defense Responses of Two Sentinel Species to Nanomaterials in the Environment

Kornélia Bodó, Nicoló Baranzini, Rossana Girardello, Bohdana Kokhanyuk, Péter Németh, Yuya Hayashi, Annalisa Grimaldi^*, Péter Engelmann^*

^*Corresponding author for this work

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

Abstract

Earthworms and leeches are sentinel animals that represent the annelid phylum within terrestrial and freshwater ecosystems, respectively. One early stress signal in these organisms is related to innate immunity, but how nanomaterials affect it is poorly characterized. In this survey, we compare the latest literature on earthworm and leeches with examples of their molecular/cellular responses to inorganic (silver nanoparticles) and organic (carbon nanotubes) nanomaterials. A special focus is placed on the role of annelid immunocytes in the evolutionarily conserved antioxidant and immune mechanisms and protein corona formation and probable endocytosis pathways involved in nanomaterial uptake. Our summary helps to realize why these environmental sentinels are beneficial to study the potential detrimental effects of nanomaterials.

Original language	English
Article number	307
Journal	Biology
Volume	9
Issue	10
Pages (from-to)	1-22
Number of pages	22
ISSN	2079-7737
DOIs	https://doi.org/10.3390/biology9100307
Publication status	Published - Oct 2020

Keywords

Earthworms
Innate immunity
Leeches
Nanoparticles
Stress

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10.3390/biology9100307

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title = "Nanomaterials and Annelid Immunity:: A Comparative Survey to Reveal the Common Stress and Defense Responses of Two Sentinel Species to Nanomaterials in the Environment",

abstract = "Earthworms and leeches are sentinel animals that represent the annelid phylum within terrestrial and freshwater ecosystems, respectively. One early stress signal in these organisms is related to innate immunity, but how nanomaterials affect it is poorly characterized. In this survey, we compare the latest literature on earthworm and leeches with examples of their molecular/cellular responses to inorganic (silver nanoparticles) and organic (carbon nanotubes) nanomaterials. A special focus is placed on the role of annelid immunocytes in the evolutionarily conserved antioxidant and immune mechanisms and protein corona formation and probable endocytosis pathways involved in nanomaterial uptake. Our summary helps to realize why these environmental sentinels are beneficial to study the potential detrimental effects of nanomaterials.",

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author = "Korn{\'e}lia Bod{\'o} and Nicol{\'o} Baranzini and Rossana Girardello and Bohdana Kokhanyuk and P{\'e}ter N{\'e}meth and Yuya Hayashi and Annalisa Grimaldi and P{\'e}ter Engelmann",

year = "2020",

month = oct,

doi = "10.3390/biology9100307",

language = "English",

volume = "9",

pages = "1--22",

journal = "Biology",

issn = "2079-7737",

publisher = "MDPI AG",

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}

Nanomaterials and Annelid Immunity: A Comparative Survey to Reveal the Common Stress and Defense Responses of Two Sentinel Species to Nanomaterials in the Environment. / Bodó, Kornélia; Baranzini, Nicoló; Girardello, Rossana et al.
In: Biology, Vol. 9, No. 10, 307, 10.2020, p. 1-22.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review

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T2 - A Comparative Survey to Reveal the Common Stress and Defense Responses of Two Sentinel Species to Nanomaterials in the Environment

AU - Bodó, Kornélia

AU - Baranzini, Nicoló

AU - Girardello, Rossana

AU - Kokhanyuk, Bohdana

AU - Németh, Péter

AU - Hayashi, Yuya

AU - Grimaldi, Annalisa

AU - Engelmann, Péter

PY - 2020/10

Y1 - 2020/10

N2 - Earthworms and leeches are sentinel animals that represent the annelid phylum within terrestrial and freshwater ecosystems, respectively. One early stress signal in these organisms is related to innate immunity, but how nanomaterials affect it is poorly characterized. In this survey, we compare the latest literature on earthworm and leeches with examples of their molecular/cellular responses to inorganic (silver nanoparticles) and organic (carbon nanotubes) nanomaterials. A special focus is placed on the role of annelid immunocytes in the evolutionarily conserved antioxidant and immune mechanisms and protein corona formation and probable endocytosis pathways involved in nanomaterial uptake. Our summary helps to realize why these environmental sentinels are beneficial to study the potential detrimental effects of nanomaterials.

AB - Earthworms and leeches are sentinel animals that represent the annelid phylum within terrestrial and freshwater ecosystems, respectively. One early stress signal in these organisms is related to innate immunity, but how nanomaterials affect it is poorly characterized. In this survey, we compare the latest literature on earthworm and leeches with examples of their molecular/cellular responses to inorganic (silver nanoparticles) and organic (carbon nanotubes) nanomaterials. A special focus is placed on the role of annelid immunocytes in the evolutionarily conserved antioxidant and immune mechanisms and protein corona formation and probable endocytosis pathways involved in nanomaterial uptake. Our summary helps to realize why these environmental sentinels are beneficial to study the potential detrimental effects of nanomaterials.

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KW - Innate immunity

KW - Leeches

KW - Nanoparticles

KW - Stress

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U2 - 10.3390/biology9100307

DO - 10.3390/biology9100307

M3 - Journal article

C2 - 32977601

SN - 2079-7737

VL - 9

SP - 1

EP - 22

JO - Biology

JF - Biology

IS - 10

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ER -

Nanomaterials and Annelid Immunity: A Comparative Survey to Reveal the Common Stress and Defense Responses of Two Sentinel Species to Nanomaterials in the Environment

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Keywords

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