N for AsN - O for StrOcture? A strand-loop-strand motif for prokaryotic O-glycosylation

TY - JOUR

T1 - N for AsN - O for StrOcture? A strand-loop-strand motif for prokaryotic O-glycosylation

AU - Otzen, Daniel

N1 - © 2012 Blackwell Publishing Ltd.

PY - 2012

Y1 - 2012

N2 - So far, it has not been possible to identify a general sequence motif for O-glycosylation in bacteria. In this issue, Charbonneau et al. demonstrate why O-glycosylation is mediated by a 13-residue strand-loop-strand motif which is part of a 19-residue imperfect repeat in the passenger domain of bacterial autotransporters. This motif provides a convenient 'glycosylation cassette' and raises intriguing questions about the structural regulation of the glycosylation pathway.

AB - So far, it has not been possible to identify a general sequence motif for O-glycosylation in bacteria. In this issue, Charbonneau et al. demonstrate why O-glycosylation is mediated by a 13-residue strand-loop-strand motif which is part of a 19-residue imperfect repeat in the passenger domain of bacterial autotransporters. This motif provides a convenient 'glycosylation cassette' and raises intriguing questions about the structural regulation of the glycosylation pathway.

U2 - 10.1111/j.1365-2958.2012.07972.x

DO - 10.1111/j.1365-2958.2012.07972.x

M3 - Journal article

C2 - 22221153

SN - 2041-1006

JO - Molecular Oral Microbiology

JF - Molecular Oral Microbiology

ER -