miRConnect 2.0: identification of oncogenic, antagonistic miRNA families in three human cancers

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miRConnect 2.0 : identification of oncogenic, antagonistic miRNA families in three human cancers. / Hua, Youjia; Larsen, Niels; Kalyana-Sundaram, Shanker; Kjems, Jørgen; Chinnaiyan, Arul M; Peter, Marcus E.

In: B M C Genomics, Vol. 14, No. 179, 15.03.2013, p. 1-18.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Hua, Y, Larsen, N, Kalyana-Sundaram, S, Kjems, J, Chinnaiyan, AM & Peter, ME 2013, 'miRConnect 2.0: identification of oncogenic, antagonistic miRNA families in three human cancers', B M C Genomics, vol. 14, no. 179, pp. 1-18. https://doi.org/10.1186/1471-2164-14-179

APA

Hua, Y., Larsen, N., Kalyana-Sundaram, S., Kjems, J., Chinnaiyan, A. M., & Peter, M. E. (2013). miRConnect 2.0: identification of oncogenic, antagonistic miRNA families in three human cancers. B M C Genomics, 14(179), 1-18. https://doi.org/10.1186/1471-2164-14-179

CBE

MLA

Vancouver

Author

Hua, Youjia ; Larsen, Niels ; Kalyana-Sundaram, Shanker ; Kjems, Jørgen ; Chinnaiyan, Arul M ; Peter, Marcus E. / miRConnect 2.0 : identification of oncogenic, antagonistic miRNA families in three human cancers. In: B M C Genomics. 2013 ; Vol. 14, No. 179. pp. 1-18.

Bibtex

@article{f67b1be7de7d430887f1e55cadba3cc1,
title = "miRConnect 2.0: identification of oncogenic, antagonistic miRNA families in three human cancers",
abstract = "Based on their function in cancer micro(mi)RNAs are often grouped as either tumor suppressors or oncogenes. However, miRNAs regulate multiple tumor relevant signaling pathways raising the question whether two oncogenic miRNAs could be functional antagonists by promoting different steps in tumor progression. We recently developed a method to connect miRNAs to biological function by comparing miRNA and gene array expression data from the NCI60 cell lines without using miRNA target predictions (miRConnect).",
keywords = "Carcinoma, Renal Cell, Cell Line, Tumor, Cluster Analysis, Epithelial-Mesenchymal Transition, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Glioblastoma, Humans, Kidney Neoplasms, MicroRNAs, Neoplasms, Oncogenes, Ovarian Neoplasms, RNA, Messenger",
author = "Youjia Hua and Niels Larsen and Shanker Kalyana-Sundaram and J{\o}rgen Kjems and Chinnaiyan, {Arul M} and Peter, {Marcus E}",
year = "2013",
month = "3",
day = "15",
doi = "10.1186/1471-2164-14-179",
language = "English",
volume = "14",
pages = "1--18",
journal = "B M C Genomics",
issn = "1471-2164",
publisher = "BioMed Central Ltd.",
number = "179",

}

RIS

TY - JOUR

T1 - miRConnect 2.0

T2 - identification of oncogenic, antagonistic miRNA families in three human cancers

AU - Hua, Youjia

AU - Larsen, Niels

AU - Kalyana-Sundaram, Shanker

AU - Kjems, Jørgen

AU - Chinnaiyan, Arul M

AU - Peter, Marcus E

PY - 2013/3/15

Y1 - 2013/3/15

N2 - Based on their function in cancer micro(mi)RNAs are often grouped as either tumor suppressors or oncogenes. However, miRNAs regulate multiple tumor relevant signaling pathways raising the question whether two oncogenic miRNAs could be functional antagonists by promoting different steps in tumor progression. We recently developed a method to connect miRNAs to biological function by comparing miRNA and gene array expression data from the NCI60 cell lines without using miRNA target predictions (miRConnect).

AB - Based on their function in cancer micro(mi)RNAs are often grouped as either tumor suppressors or oncogenes. However, miRNAs regulate multiple tumor relevant signaling pathways raising the question whether two oncogenic miRNAs could be functional antagonists by promoting different steps in tumor progression. We recently developed a method to connect miRNAs to biological function by comparing miRNA and gene array expression data from the NCI60 cell lines without using miRNA target predictions (miRConnect).

KW - Carcinoma, Renal Cell

KW - Cell Line, Tumor

KW - Cluster Analysis

KW - Epithelial-Mesenchymal Transition

KW - Female

KW - Gene Expression Profiling

KW - Gene Expression Regulation, Neoplastic

KW - Glioblastoma

KW - Humans

KW - Kidney Neoplasms

KW - MicroRNAs

KW - Neoplasms

KW - Oncogenes

KW - Ovarian Neoplasms

KW - RNA, Messenger

U2 - 10.1186/1471-2164-14-179

DO - 10.1186/1471-2164-14-179

M3 - Journal article

C2 - 23497354

VL - 14

SP - 1

EP - 18

JO - B M C Genomics

JF - B M C Genomics

SN - 1471-2164

IS - 179

ER -