TY - JOUR
T1 - Mechanistic Effect Modeling of Earthworms in the Context of Pesticide Risk Assessment
T2 - Synthesis of the FORESEE Workshop
AU - Forbes, Valery E.
AU - Agatz, Annika
AU - Ashauer, Roman
AU - Butt, Kevin R.
AU - Capowiez, Yvan
AU - Duquesne, Sabine
AU - Ernst, Gregor
AU - Focks, Andreas
AU - Gergs, Andre
AU - Hodson, Mark E.
AU - Holmstrup, Martin
AU - Johnston, Alice S.A.
AU - Meli, Mattia
AU - Nickisch, Dirk
AU - Pieper, Silvia
AU - Rakel, Kim J.
AU - Reed, Melissa
AU - Roembke, Joerg
AU - Schäfer, Ralf B.
AU - Thorbek, Pernille
AU - Spurgeon, David J.
AU - Van den Berg, Erik
AU - Van Gestel, Cornelis A.M.
AU - Zorn, Mathilde I.
AU - Roeben, Vanessa
PY - 2021/3
Y1 - 2021/3
N2 - Earthworms are important ecosystem engineers, and assessment of the risk of plant protection products toward them is part of the European environmental risk assessment (ERA). In the current ERA scheme, exposure and effects are represented simplistically and are not well integrated, resulting in uncertainty when the results are applied to ecosystems. Modeling offers a powerful tool to integrate the effects observed in lower tier laboratory studies with the environmental conditions under which exposure is expected in the field. This paper provides a summary of the (In)Field Organism Risk modEling by coupling Soil Exposure and Effect (FORESEE) Workshop held 28–30 January 2020 in Düsseldorf, Germany. This workshop focused on toxicokinetic–toxicodynamic (TKTD) and population modeling of earthworms in the context of ERA. The goal was to bring together scientists from different stakeholder groups to discuss the current state of soil invertebrate modeling and to explore how earthworm modeling could be applied to risk assessments, in particular how the different model outputs can be used in the tiered ERA approach. In support of these goals, the workshop aimed at addressing the requirements and concerns of the different stakeholder groups to support further model development. The modeling approach included 4 submodules to cover the most relevant processes for earthworm risk assessment: environment, behavior (feeding, vertical movement), TKTD, and population. Four workgroups examined different aspects of the model with relevance for risk assessment, earthworm ecology, uptake routes, and cross-species extrapolation and model testing. Here, we present the perspectives of each workgroup and highlight how the collaborative effort of participants from multidisciplinary backgrounds helped to establish common ground. In addition, we provide a list of recommendations for how earthworm TKTD modeling could address some of the uncertainties in current risk assessments for plant protection products. Integr Environ Assess Manag 2021;17:352–363.
AB - Earthworms are important ecosystem engineers, and assessment of the risk of plant protection products toward them is part of the European environmental risk assessment (ERA). In the current ERA scheme, exposure and effects are represented simplistically and are not well integrated, resulting in uncertainty when the results are applied to ecosystems. Modeling offers a powerful tool to integrate the effects observed in lower tier laboratory studies with the environmental conditions under which exposure is expected in the field. This paper provides a summary of the (In)Field Organism Risk modEling by coupling Soil Exposure and Effect (FORESEE) Workshop held 28–30 January 2020 in Düsseldorf, Germany. This workshop focused on toxicokinetic–toxicodynamic (TKTD) and population modeling of earthworms in the context of ERA. The goal was to bring together scientists from different stakeholder groups to discuss the current state of soil invertebrate modeling and to explore how earthworm modeling could be applied to risk assessments, in particular how the different model outputs can be used in the tiered ERA approach. In support of these goals, the workshop aimed at addressing the requirements and concerns of the different stakeholder groups to support further model development. The modeling approach included 4 submodules to cover the most relevant processes for earthworm risk assessment: environment, behavior (feeding, vertical movement), TKTD, and population. Four workgroups examined different aspects of the model with relevance for risk assessment, earthworm ecology, uptake routes, and cross-species extrapolation and model testing. Here, we present the perspectives of each workgroup and highlight how the collaborative effort of participants from multidisciplinary backgrounds helped to establish common ground. In addition, we provide a list of recommendations for how earthworm TKTD modeling could address some of the uncertainties in current risk assessments for plant protection products. Integr Environ Assess Manag 2021;17:352–363.
KW - Cross-species extrapolation
KW - Plant protection products
KW - Population modeling
KW - Soil organisms
KW - Uptake routes
UR - http://www.scopus.com/inward/record.url?scp=85093860377&partnerID=8YFLogxK
U2 - 10.1002/ieam.4338
DO - 10.1002/ieam.4338
M3 - Journal article
C2 - 32910508
AN - SCOPUS:85093860377
SN - 1551-3793
VL - 17
SP - 352
EP - 363
JO - Integrated Environmental Assessment and Management
JF - Integrated Environmental Assessment and Management
IS - 2
ER -