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Mast cell FcϵRI density and function dissociate from dependence on soluble IgE concentration at very low and very high IgE concentrations

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Mast cell FcϵRI density and function dissociate from dependence on soluble IgE concentration at very low and very high IgE concentrations. / Krohn, Inge Kortekaas; Lund, Gitte; Frandsen, Pernille Munk; Schiøtz, Peter Oluf; Dahl, Ronald; Hoffmann, Hans Jürgen.

In: Journal of Asthma, Vol. 50, No. 2, 03.2013, p. 117-21.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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Author

Krohn, Inge Kortekaas ; Lund, Gitte ; Frandsen, Pernille Munk ; Schiøtz, Peter Oluf ; Dahl, Ronald ; Hoffmann, Hans Jürgen. / Mast cell FcϵRI density and function dissociate from dependence on soluble IgE concentration at very low and very high IgE concentrations. In: Journal of Asthma. 2013 ; Vol. 50, No. 2. pp. 117-21.

Bibtex

@article{11364fe799e1437397fda6b6dff49b4f,
title = "Mast cell FcϵRI density and function dissociate from dependence on soluble IgE concentration at very low and very high IgE concentrations",
abstract = "The contribution of affinity, clonality, and concentration of individual IgE species to effector cell response has recently been characterized in a model with recombinant human IgE on passively sensitized basophils. This study extends the dependence of effector cell degranulation on IgE concentration to mast cells cultured with IgE for 2 weeks.",
keywords = "Antigens, CD63, Antigens, Dermatophagoides, Cell Degranulation, Histamine Release, Humans, Hypersensitivity, Immunoglobulin E, Leukocytes, Mononuclear, Mast Cells, Prostaglandin D2, Receptors, IgG, Statistics, Nonparametric",
author = "Krohn, {Inge Kortekaas} and Gitte Lund and Frandsen, {Pernille Munk} and Schi{\o}tz, {Peter Oluf} and Ronald Dahl and Hoffmann, {Hans J{\"u}rgen}",
year = "2013",
month = mar,
doi = "10.3109/02770903.2012.752504",
language = "English",
volume = "50",
pages = "117--21",
journal = "Journal of Asthma",
issn = "0277-0903",
publisher = "Taylor & Francis Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - Mast cell FcϵRI density and function dissociate from dependence on soluble IgE concentration at very low and very high IgE concentrations

AU - Krohn, Inge Kortekaas

AU - Lund, Gitte

AU - Frandsen, Pernille Munk

AU - Schiøtz, Peter Oluf

AU - Dahl, Ronald

AU - Hoffmann, Hans Jürgen

PY - 2013/3

Y1 - 2013/3

N2 - The contribution of affinity, clonality, and concentration of individual IgE species to effector cell response has recently been characterized in a model with recombinant human IgE on passively sensitized basophils. This study extends the dependence of effector cell degranulation on IgE concentration to mast cells cultured with IgE for 2 weeks.

AB - The contribution of affinity, clonality, and concentration of individual IgE species to effector cell response has recently been characterized in a model with recombinant human IgE on passively sensitized basophils. This study extends the dependence of effector cell degranulation on IgE concentration to mast cells cultured with IgE for 2 weeks.

KW - Antigens, CD63

KW - Antigens, Dermatophagoides

KW - Cell Degranulation

KW - Histamine Release

KW - Humans

KW - Hypersensitivity

KW - Immunoglobulin E

KW - Leukocytes, Mononuclear

KW - Mast Cells

KW - Prostaglandin D2

KW - Receptors, IgG

KW - Statistics, Nonparametric

U2 - 10.3109/02770903.2012.752504

DO - 10.3109/02770903.2012.752504

M3 - Journal article

C2 - 23294195

VL - 50

SP - 117

EP - 121

JO - Journal of Asthma

JF - Journal of Asthma

SN - 0277-0903

IS - 2

ER -