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Mangel på mannan-bindende protein--et nyopdaget komplementdefektsyndrom

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Mannan-binding protein (MBP) is a newly discovered serum protein which activates the complement system by the classical pathway by binding to mannose-rich surfaces on microorganisms. MBP deficiency predisposes to infection in infancy. MBP is a C-type lectin with collagen structure, a so-called collection. The paper discusses the structure and physiological functions of MBP. MBP may be an important parameter in the investigation of immunodeficiencies in children.
Translated title of the contribution[Deficiency of mannan-binding protein--a recently discovered complement defect syndrome]
Original languageDanish
JournalUgeskrift for Laeger
Pages (from-to)25-9
Number of pages5
Publication statusPublished - 1993

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