Management of neuropathic pain.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

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Management of neuropathic pain. / Jensen, Troels S; Finnerup, Nanna Brix.

In: Current Opinion in Supportive and Palliative Care, Vol. 1, No. 2, 2007, p. 126-31.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

Harvard

Jensen, TS & Finnerup, NB 2007, 'Management of neuropathic pain.', Current Opinion in Supportive and Palliative Care, vol. 1, no. 2, pp. 126-31. https://doi.org/10.1097/SPC.0b013e3282eeb45f

APA

Jensen, T. S., & Finnerup, N. B. (2007). Management of neuropathic pain. Current Opinion in Supportive and Palliative Care, 1(2), 126-31. https://doi.org/10.1097/SPC.0b013e3282eeb45f

CBE

Jensen TS, Finnerup NB. 2007. Management of neuropathic pain. Current Opinion in Supportive and Palliative Care. 1(2):126-31. https://doi.org/10.1097/SPC.0b013e3282eeb45f

MLA

Vancouver

Jensen TS, Finnerup NB. Management of neuropathic pain. Current Opinion in Supportive and Palliative Care. 2007;1(2):126-31. https://doi.org/10.1097/SPC.0b013e3282eeb45f

Author

Jensen, Troels S ; Finnerup, Nanna Brix. / Management of neuropathic pain. In: Current Opinion in Supportive and Palliative Care. 2007 ; Vol. 1, No. 2. pp. 126-31.

Bibtex

@article{cd7c4420a4d711dd889c000ea68e967b,
title = "Management of neuropathic pain.",
abstract = "PURPOSE OF REVIEW: Neuropathic pain is a chronic pain condition arising from injury or disease of the peripheral or central nervous system with a substantial impact on quality of life. This brief review focuses on the increasing evidence for effective treatments and discusses an evidence-based algorithm for treating neuropathic pain conditions. RECENT FINDINGS: Randomized controlled trials have consistently shown efficacy of tricyclic antidepressants, gabapentin/pregabalin, opioids, tramadol, and serotonin and noradrenaline-reuptake inhibitors for the treatment of various neuropathic pain conditions, lidocaine patches for postherpetic neuralgia and cannabinoids for pain in multiple sclerosis. Carbamazepine or oxcarbazepine is the treatment of choice for trigeminal neuralgia. The efficacy of these drugs in other neuropathic pain conditions as well as the efficacy of lamotrigine and topical capsaicin is questionable, but they may be useful in a subgroup of patients. SUMMARY: For each patient, considerations on the underlying pain mechanisms, immediate and potential long-term side effects, and price as well as comorbidities and concurrent medications will decide which drug should be the first choice, but until further progress is made towards a mechanism-based classification, treatment is likely to be a trial-and-error process where drug combinations may also be considered.",
keywords = "Analgesics, Opioid, Anticonvulsants, Antidepressive Agents, Tricyclic, Peripheral Nervous System Diseases, Randomized Controlled Trials as Topic",
author = "Jensen, {Troels S} and Finnerup, {Nanna Brix}",
year = "2007",
doi = "10.1097/SPC.0b013e3282eeb45f",
language = "English",
volume = "1",
pages = "126--31",
journal = "Current Opinion in Supportive and Palliative Care",
issn = "1751-4258",
publisher = "Lippincott Williams & Wilkins, Ltd.",
number = "2",

}

RIS

TY - JOUR

T1 - Management of neuropathic pain.

AU - Jensen, Troels S

AU - Finnerup, Nanna Brix

PY - 2007

Y1 - 2007

N2 - PURPOSE OF REVIEW: Neuropathic pain is a chronic pain condition arising from injury or disease of the peripheral or central nervous system with a substantial impact on quality of life. This brief review focuses on the increasing evidence for effective treatments and discusses an evidence-based algorithm for treating neuropathic pain conditions. RECENT FINDINGS: Randomized controlled trials have consistently shown efficacy of tricyclic antidepressants, gabapentin/pregabalin, opioids, tramadol, and serotonin and noradrenaline-reuptake inhibitors for the treatment of various neuropathic pain conditions, lidocaine patches for postherpetic neuralgia and cannabinoids for pain in multiple sclerosis. Carbamazepine or oxcarbazepine is the treatment of choice for trigeminal neuralgia. The efficacy of these drugs in other neuropathic pain conditions as well as the efficacy of lamotrigine and topical capsaicin is questionable, but they may be useful in a subgroup of patients. SUMMARY: For each patient, considerations on the underlying pain mechanisms, immediate and potential long-term side effects, and price as well as comorbidities and concurrent medications will decide which drug should be the first choice, but until further progress is made towards a mechanism-based classification, treatment is likely to be a trial-and-error process where drug combinations may also be considered.

AB - PURPOSE OF REVIEW: Neuropathic pain is a chronic pain condition arising from injury or disease of the peripheral or central nervous system with a substantial impact on quality of life. This brief review focuses on the increasing evidence for effective treatments and discusses an evidence-based algorithm for treating neuropathic pain conditions. RECENT FINDINGS: Randomized controlled trials have consistently shown efficacy of tricyclic antidepressants, gabapentin/pregabalin, opioids, tramadol, and serotonin and noradrenaline-reuptake inhibitors for the treatment of various neuropathic pain conditions, lidocaine patches for postherpetic neuralgia and cannabinoids for pain in multiple sclerosis. Carbamazepine or oxcarbazepine is the treatment of choice for trigeminal neuralgia. The efficacy of these drugs in other neuropathic pain conditions as well as the efficacy of lamotrigine and topical capsaicin is questionable, but they may be useful in a subgroup of patients. SUMMARY: For each patient, considerations on the underlying pain mechanisms, immediate and potential long-term side effects, and price as well as comorbidities and concurrent medications will decide which drug should be the first choice, but until further progress is made towards a mechanism-based classification, treatment is likely to be a trial-and-error process where drug combinations may also be considered.

KW - Analgesics, Opioid

KW - Anticonvulsants

KW - Antidepressive Agents, Tricyclic

KW - Peripheral Nervous System Diseases

KW - Randomized Controlled Trials as Topic

U2 - 10.1097/SPC.0b013e3282eeb45f

DO - 10.1097/SPC.0b013e3282eeb45f

M3 - Review

C2 - 18685353

VL - 1

SP - 126

EP - 131

JO - Current Opinion in Supportive and Palliative Care

JF - Current Opinion in Supportive and Palliative Care

SN - 1751-4258

IS - 2

ER -