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Male sleep duration and fecundability in a North American preconception cohort study

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Male sleep duration and fecundability in a North American preconception cohort study. / Wise, Lauren Anne; Rothman, Kenneth Jay; Wesselink, Amelia Kent; Mikkelsen, Ellen Margrethe; Sorensen, Henrik Toft; McKinnon, Craig James; Hatch, Elizabeth Elliott.

In: Fertility and Sterility, Vol. 109, No. 3, 03.2018, p. 453-459.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Wise, LA, Rothman, KJ, Wesselink, AK, Mikkelsen, EM, Sorensen, HT, McKinnon, CJ & Hatch, EE 2018, 'Male sleep duration and fecundability in a North American preconception cohort study', Fertility and Sterility, vol. 109, no. 3, pp. 453-459. https://doi.org/10.1016/j.fertnstert.2017.11.037

APA

Wise, L. A., Rothman, K. J., Wesselink, A. K., Mikkelsen, E. M., Sorensen, H. T., McKinnon, C. J., & Hatch, E. E. (2018). Male sleep duration and fecundability in a North American preconception cohort study. Fertility and Sterility, 109(3), 453-459. https://doi.org/10.1016/j.fertnstert.2017.11.037

CBE

MLA

Vancouver

Author

Wise, Lauren Anne ; Rothman, Kenneth Jay ; Wesselink, Amelia Kent ; Mikkelsen, Ellen Margrethe ; Sorensen, Henrik Toft ; McKinnon, Craig James ; Hatch, Elizabeth Elliott. / Male sleep duration and fecundability in a North American preconception cohort study. In: Fertility and Sterility. 2018 ; Vol. 109, No. 3. pp. 453-459.

Bibtex

@article{ab748213137049c98ff9aed6b44a4e6c,
title = "Male sleep duration and fecundability in a North American preconception cohort study",
abstract = "OBJECTIVE: To evaluate prospectively the association between male sleep duration and fecundability.DESIGN: Pregnancy Online Study (PRESTO), a Web-based prospective cohort study of North American couples enrolled during the preconception period (2013-2017).SETTING: Not applicable.PATIENT(S): Male participants were aged ≥21 years; female participants were aged 21-45 years.INTERVENTION(S): None.MAIN OUTCOME MEASURE(S): At enrollment, men reported their average nightly sleep duration in the previous month. Pregnancy status was updated on female follow-up questionnaires every 8 weeks for up to 12 months or until conception. Analyses were restricted to 1,176 couples who had been attempting to conceive for up to six cycles at enrollment. Proportional probabilities regression models were used to estimate fecundability ratios (FRs) and 95{\%} confidence intervals (CIs), adjusting for potential confounders.RESULT(S): Relative to 8 hours per night of sleep, multivariable-adjusted FRs for <6, 6, 7, and ≥9 hours per night of sleep were 0.62 (95{\%} CI 0.45-0.87), 1.06 (95{\%} CI 0.87-1.30), 0.97 (95{\%} CI 0.81-1.17), and 0.73 (95{\%} CI 0.46-1.15), respectively. The association between short sleep duration (<6 hours per night) and fecundability was similar among men not working nights or rotating shifts (FR 0.60, 95{\%} CI 0.41-0.88) and among men without a history of infertility (FR 0.62, 95{\%} CI 0.44-0.87) and was stronger among fathers (FR 0.46, 95{\%} CI 0.28-0.76).CONCLUSION(S): Short sleep duration in men was associated with reduced fecundability. Because male factor accounts for 50{\%} of couple infertility, identifying modifiable determinants of infertility could provide alternatives to expensive fertility workups and treatments.",
author = "Wise, {Lauren Anne} and Rothman, {Kenneth Jay} and Wesselink, {Amelia Kent} and Mikkelsen, {Ellen Margrethe} and Sorensen, {Henrik Toft} and McKinnon, {Craig James} and Hatch, {Elizabeth Elliott}",
note = "Copyright {\circledC} 2017 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.",
year = "2018",
month = "3",
doi = "10.1016/j.fertnstert.2017.11.037",
language = "English",
volume = "109",
pages = "453--459",
journal = "Fertility and Sterility",
issn = "0015-0282",
publisher = "Elsevier Inc",
number = "3",

}

RIS

TY - JOUR

T1 - Male sleep duration and fecundability in a North American preconception cohort study

AU - Wise, Lauren Anne

AU - Rothman, Kenneth Jay

AU - Wesselink, Amelia Kent

AU - Mikkelsen, Ellen Margrethe

AU - Sorensen, Henrik Toft

AU - McKinnon, Craig James

AU - Hatch, Elizabeth Elliott

N1 - Copyright © 2017 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

PY - 2018/3

Y1 - 2018/3

N2 - OBJECTIVE: To evaluate prospectively the association between male sleep duration and fecundability.DESIGN: Pregnancy Online Study (PRESTO), a Web-based prospective cohort study of North American couples enrolled during the preconception period (2013-2017).SETTING: Not applicable.PATIENT(S): Male participants were aged ≥21 years; female participants were aged 21-45 years.INTERVENTION(S): None.MAIN OUTCOME MEASURE(S): At enrollment, men reported their average nightly sleep duration in the previous month. Pregnancy status was updated on female follow-up questionnaires every 8 weeks for up to 12 months or until conception. Analyses were restricted to 1,176 couples who had been attempting to conceive for up to six cycles at enrollment. Proportional probabilities regression models were used to estimate fecundability ratios (FRs) and 95% confidence intervals (CIs), adjusting for potential confounders.RESULT(S): Relative to 8 hours per night of sleep, multivariable-adjusted FRs for <6, 6, 7, and ≥9 hours per night of sleep were 0.62 (95% CI 0.45-0.87), 1.06 (95% CI 0.87-1.30), 0.97 (95% CI 0.81-1.17), and 0.73 (95% CI 0.46-1.15), respectively. The association between short sleep duration (<6 hours per night) and fecundability was similar among men not working nights or rotating shifts (FR 0.60, 95% CI 0.41-0.88) and among men without a history of infertility (FR 0.62, 95% CI 0.44-0.87) and was stronger among fathers (FR 0.46, 95% CI 0.28-0.76).CONCLUSION(S): Short sleep duration in men was associated with reduced fecundability. Because male factor accounts for 50% of couple infertility, identifying modifiable determinants of infertility could provide alternatives to expensive fertility workups and treatments.

AB - OBJECTIVE: To evaluate prospectively the association between male sleep duration and fecundability.DESIGN: Pregnancy Online Study (PRESTO), a Web-based prospective cohort study of North American couples enrolled during the preconception period (2013-2017).SETTING: Not applicable.PATIENT(S): Male participants were aged ≥21 years; female participants were aged 21-45 years.INTERVENTION(S): None.MAIN OUTCOME MEASURE(S): At enrollment, men reported their average nightly sleep duration in the previous month. Pregnancy status was updated on female follow-up questionnaires every 8 weeks for up to 12 months or until conception. Analyses were restricted to 1,176 couples who had been attempting to conceive for up to six cycles at enrollment. Proportional probabilities regression models were used to estimate fecundability ratios (FRs) and 95% confidence intervals (CIs), adjusting for potential confounders.RESULT(S): Relative to 8 hours per night of sleep, multivariable-adjusted FRs for <6, 6, 7, and ≥9 hours per night of sleep were 0.62 (95% CI 0.45-0.87), 1.06 (95% CI 0.87-1.30), 0.97 (95% CI 0.81-1.17), and 0.73 (95% CI 0.46-1.15), respectively. The association between short sleep duration (<6 hours per night) and fecundability was similar among men not working nights or rotating shifts (FR 0.60, 95% CI 0.41-0.88) and among men without a history of infertility (FR 0.62, 95% CI 0.44-0.87) and was stronger among fathers (FR 0.46, 95% CI 0.28-0.76).CONCLUSION(S): Short sleep duration in men was associated with reduced fecundability. Because male factor accounts for 50% of couple infertility, identifying modifiable determinants of infertility could provide alternatives to expensive fertility workups and treatments.

U2 - 10.1016/j.fertnstert.2017.11.037

DO - 10.1016/j.fertnstert.2017.11.037

M3 - Journal article

C2 - 29566862

VL - 109

SP - 453

EP - 459

JO - Fertility and Sterility

JF - Fertility and Sterility

SN - 0015-0282

IS - 3

ER -