Macromolecular Prodrugs of Ribavirin: Concerted Efforts of the Carrier and the Drug

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • Anton A A Smith
  • Benjamin M Wohl, Denmark
  • Mille B L Kryger, Denmark
  • Natasha Hedemann, Denmark
  • Carlos Guerrero-Sanchez, CSIRO – Materials Science and Engineering, Ian Wark Laboratory
  • ,
  • Almar Postma, CSIRO – Materials Science and Engineering, Ian Wark Laboratory
  • ,
  • Alexander N. Zelikin
Polymers in tune. Automated parallel polymer synthesis is developed to obtain libraries of macromolecular prodrugs of ribavirin, a broad-spectrum antiviral agent. As many as 10 identified lead polymer conjugates exhibit therapeutic efficacy matching that of the pristine drug and at the same time suppressed the origin of the main side effect of ribavirin.
Original languageEnglish
JournalAdvanced Healthcare Materials
Volume3
Issue9
Pages (from-to)1404-1407
Number of pages4
ISSN2192-2640
DOIs
Publication statusPublished - 10 Jan 2014

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