Lotus Base: An integrated information portal for the model legume Lotus japonicus

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review


  • srep39447

    Final published version, 1.99 MB, PDF document


Lotus japonicus is a well-characterized model legume widely used in the study of plant-microbe interactions. However, datasets from various Lotus studies are poorly integrated and lack interoperability. We recognize the need for a comprehensive repository that allows comprehensive and dynamic exploration of Lotus genomic and transcriptomic data. Equally important are user-friendly in-browser tools designed for data visualization and interpretation. Here, we present Lotus Base, which opens to the research community a large, established LORE1 insertion mutant population containing an excess of 120,000 lines, and serves the end-user tightly integrated data from Lotus, such as the reference genome, annotated proteins, and expression profiling data. We report the integration of expression data from the L. japonicus gene expression atlas project, and the development of tools to cluster and export such data, allowing users to construct, visualize, and annotate co-expression gene networks. Lotus Base takes advantage of modern advances in browser technology to deliver powerful data interpretation for biologists. Its modular construction and publicly available application programming interface enable developers to tap into the wealth of integrated Lotus data. Lotus Base is freely accessible at: https://lotus.au.dk.
Original languageEnglish
Article number39447
JournalScientific Reports
Publication statusPublished - 23 Dec 2016

    Research areas

  • Bioinformatics, Data Mining, insertion mutagenesis, LORE1, Lotus japonicus, Gene expression profile, Co-expression network, Molecular Biology, Plant biology, Database, Web technology

See relations at Aarhus University Citationformats

Download statistics

No data available

ID: 107494121