Long-term outcome of patients with DSWI following cardiac surgery – preliminary results from the SWEDEHEART registry

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Standard

Long-term outcome of patients with DSWI following cardiac surgery – preliminary results from the SWEDEHEART registry. / Kaspersen, Alexander Emil; Nielsen, Susanne J.; Petursdottir, Astridur; Sigurdsson, Martin Ingi; Jeppsson, Anders; Gudbjartsson, Tomas.

2019. Abstract from 3rd Annual Research Meeting at the Department of Clinical Medicine .

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Harvard

Kaspersen, AE, Nielsen, SJ, Petursdottir, A, Sigurdsson, MI, Jeppsson, A & Gudbjartsson, T 2019, 'Long-term outcome of patients with DSWI following cardiac surgery – preliminary results from the SWEDEHEART registry', 3rd Annual Research Meeting at the Department of Clinical Medicine , 27/11/2019 - 27/11/2019.

APA

Kaspersen, A. E., Nielsen, S. J., Petursdottir, A., Sigurdsson, M. I., Jeppsson, A., & Gudbjartsson, T. (2019). Long-term outcome of patients with DSWI following cardiac surgery – preliminary results from the SWEDEHEART registry. Abstract from 3rd Annual Research Meeting at the Department of Clinical Medicine .

CBE

Kaspersen AE, Nielsen SJ, Petursdottir A, Sigurdsson MI, Jeppsson A, Gudbjartsson T. 2019. Long-term outcome of patients with DSWI following cardiac surgery – preliminary results from the SWEDEHEART registry. Abstract from 3rd Annual Research Meeting at the Department of Clinical Medicine .

MLA

Kaspersen, Alexander Emil et al. Long-term outcome of patients with DSWI following cardiac surgery – preliminary results from the SWEDEHEART registry. 3rd Annual Research Meeting at the Department of Clinical Medicine , 27 Nov 2019, Conference abstract for conference, 2019.

Vancouver

Kaspersen AE, Nielsen SJ, Petursdottir A, Sigurdsson MI, Jeppsson A, Gudbjartsson T. Long-term outcome of patients with DSWI following cardiac surgery – preliminary results from the SWEDEHEART registry. 2019. Abstract from 3rd Annual Research Meeting at the Department of Clinical Medicine .

Author

Kaspersen, Alexander Emil ; Nielsen, Susanne J. ; Petursdottir, Astridur ; Sigurdsson, Martin Ingi ; Jeppsson, Anders ; Gudbjartsson, Tomas. / Long-term outcome of patients with DSWI following cardiac surgery – preliminary results from the SWEDEHEART registry. Abstract from 3rd Annual Research Meeting at the Department of Clinical Medicine .

Bibtex

@conference{f2aecc20a6a04ff6b1a0150eed2cb90f,
title = "Long-term outcome of patients with DSWI following cardiac surgery – preliminary results from the SWEDEHEART registry",
abstract = "Deep sternal wound infection (DSWI) is a major complication following open heart surgery with increased mortality and morbidity for the patient. The incidence is usually 1-4% and 90-days mortality 0-16%. Numerous studies have analyzed short-term outcome of DSWI and defined risk factors. However, less is known about long-term survival and complications of these patients. We therefore studied long-term outcome of DSWI patients in a large nation-wide cohort of heart surgery patients.This retrospective cohort study included 114,869 patients from the SWEDEHEART registry who underwent CABG (70.6%), valve repair or replacement (18.6%) or both (10.8%) between 1997 to 2015. DSWI patients were identified by surgical intervention codes in the Swedish Patient Registry (reoperation for deep infection), and DSWI cases were compared to surgical patients not developing DSWI. Median follow-up was 5.5 years for the DSWI cases and 8.0 years for the non-infected patients.Altogether, 1,516 patients (1.3%) developed DSWI, most of them after CABG (69.7%). Median time from surgery to surgical intervention was 15 days (range 0-90 days). DSWI patients were older and had significantly higher BMI than those without. They had more often diabetes, hypertension, heart failure, previous stroke, renal failure and more often underwent combined CABG and valve surgery. Ninety-day mortality was 7.9% vs. 3.0% (p<0.001) in the DSWI vs. non-infected group, and 1-, 5- and 10-year mortality was 12.8% vs. 4.5%, 28.9% vs. 14.1% and 57.0% vs. 33.1%, respectively (<0.001). DSWI patients had inferior unadjusted mortality compared to the group not developing the infection.In this nation-wide cohort study, the unadjusted ninety-day mortality was almost threefold higher for DSWI patients than for non-DSWI patients and long-term all-cause mortality was also significantly increased in the DSWI group.",
author = "Kaspersen, {Alexander Emil} and Nielsen, {Susanne J.} and Astridur Petursdottir and Sigurdsson, {Martin Ingi} and Anders Jeppsson and Tomas Gudbjartsson",
year = "2019",
month = nov,
day = "27",
language = "Dansk",
note = "3rd Annual Research Meeting at the Department of Clinical Medicine ; Conference date: 27-11-2019 Through 27-11-2019",

}

RIS

TY - ABST

T1 - Long-term outcome of patients with DSWI following cardiac surgery – preliminary results from the SWEDEHEART registry

AU - Kaspersen, Alexander Emil

AU - Nielsen, Susanne J.

AU - Petursdottir, Astridur

AU - Sigurdsson, Martin Ingi

AU - Jeppsson, Anders

AU - Gudbjartsson, Tomas

PY - 2019/11/27

Y1 - 2019/11/27

N2 - Deep sternal wound infection (DSWI) is a major complication following open heart surgery with increased mortality and morbidity for the patient. The incidence is usually 1-4% and 90-days mortality 0-16%. Numerous studies have analyzed short-term outcome of DSWI and defined risk factors. However, less is known about long-term survival and complications of these patients. We therefore studied long-term outcome of DSWI patients in a large nation-wide cohort of heart surgery patients.This retrospective cohort study included 114,869 patients from the SWEDEHEART registry who underwent CABG (70.6%), valve repair or replacement (18.6%) or both (10.8%) between 1997 to 2015. DSWI patients were identified by surgical intervention codes in the Swedish Patient Registry (reoperation for deep infection), and DSWI cases were compared to surgical patients not developing DSWI. Median follow-up was 5.5 years for the DSWI cases and 8.0 years for the non-infected patients.Altogether, 1,516 patients (1.3%) developed DSWI, most of them after CABG (69.7%). Median time from surgery to surgical intervention was 15 days (range 0-90 days). DSWI patients were older and had significantly higher BMI than those without. They had more often diabetes, hypertension, heart failure, previous stroke, renal failure and more often underwent combined CABG and valve surgery. Ninety-day mortality was 7.9% vs. 3.0% (p<0.001) in the DSWI vs. non-infected group, and 1-, 5- and 10-year mortality was 12.8% vs. 4.5%, 28.9% vs. 14.1% and 57.0% vs. 33.1%, respectively (<0.001). DSWI patients had inferior unadjusted mortality compared to the group not developing the infection.In this nation-wide cohort study, the unadjusted ninety-day mortality was almost threefold higher for DSWI patients than for non-DSWI patients and long-term all-cause mortality was also significantly increased in the DSWI group.

AB - Deep sternal wound infection (DSWI) is a major complication following open heart surgery with increased mortality and morbidity for the patient. The incidence is usually 1-4% and 90-days mortality 0-16%. Numerous studies have analyzed short-term outcome of DSWI and defined risk factors. However, less is known about long-term survival and complications of these patients. We therefore studied long-term outcome of DSWI patients in a large nation-wide cohort of heart surgery patients.This retrospective cohort study included 114,869 patients from the SWEDEHEART registry who underwent CABG (70.6%), valve repair or replacement (18.6%) or both (10.8%) between 1997 to 2015. DSWI patients were identified by surgical intervention codes in the Swedish Patient Registry (reoperation for deep infection), and DSWI cases were compared to surgical patients not developing DSWI. Median follow-up was 5.5 years for the DSWI cases and 8.0 years for the non-infected patients.Altogether, 1,516 patients (1.3%) developed DSWI, most of them after CABG (69.7%). Median time from surgery to surgical intervention was 15 days (range 0-90 days). DSWI patients were older and had significantly higher BMI than those without. They had more often diabetes, hypertension, heart failure, previous stroke, renal failure and more often underwent combined CABG and valve surgery. Ninety-day mortality was 7.9% vs. 3.0% (p<0.001) in the DSWI vs. non-infected group, and 1-, 5- and 10-year mortality was 12.8% vs. 4.5%, 28.9% vs. 14.1% and 57.0% vs. 33.1%, respectively (<0.001). DSWI patients had inferior unadjusted mortality compared to the group not developing the infection.In this nation-wide cohort study, the unadjusted ninety-day mortality was almost threefold higher for DSWI patients than for non-DSWI patients and long-term all-cause mortality was also significantly increased in the DSWI group.

M3 - Konferenceabstrakt til konference

T2 - 3rd Annual Research Meeting at the Department of Clinical Medicine

Y2 - 27 November 2019 through 27 November 2019

ER -