Locomotion of Micromotors Due to Liposome Disintegration

Federico Mazur, Marina Fernández-Medina, Noga Gal, Ondrej Hovorka, Rona Chandrawati, Brigitte Städler*

*Corresponding author for this work

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review


Synthetic micromotors are evaluated extensively in a range of biomedical, microscale transport, and environmental applications. Fundamental insight into micromotors that exhibit locomotion due to triggered disintegration of their associated liposomes is provided. Directed self-propulsion is observed when the lipid vesicles are solubilized using Triton X-100 (TX) and bile at sufficiently high concentrations. Directional motion, initiated by a propagating TX or bile gradient, is found when using a sufficiently high concentration of solubilization agents. On the other hand, a low bile concentration results in short-term reverse directional motion. The experimental and theoretical considerations offer valid fundamental understanding to complement the list of explored locomotion mechanisms for micromotors.

Original languageEnglish
Pages (from-to)7056-7065
Number of pages10
Publication statusPublished - Jun 2020


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