L-SeqSleepNet: Whole-cycle Long Sequence Modeling for Automatic Sleep Staging

Huy Phan*, Kristian P. Lorenzen, Elisabeth Heremans, Oliver Y. Chen, Minh C. Tran, Philipp Koch, Alfred Mertins, Mathias Baumert, Kaare B. Mikkelsen, Maarten De Vos

*Corresponding author for this work

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

30 Citations (Scopus)

Abstract

Human sleep is cyclical with a period of approximately 90 minutes, implying long temporal dependency in the sleep data. Yet, exploring this long-term dependency when developing sleep staging models has remained untouched. In this work, we show that while encoding the logic of a whole sleep cycle is crucial to improve sleep staging performance, the sequential modelling approach in existing state-of-the-art deep learning models are inefficient for that purpose. We thus introduce a method for efficient long sequence modelling and propose a new deep learning model, L-SeqSleepNet, which takes into account whole-cycle sleep information for sleep staging. Evaluating L-SeqSleepNet on four distinct databases of various sizes, we demonstrate state-of-the-art performance obtained by the model over three different EEG setups, including scalp EEG in conventional Polysomnography (PSG), in-ear EEG, and around-the-ear EEG (cEEGrid), even with a single EEG channel input. Our analyses also show that L-SeqSleepNet is able to alleviate the predominance of N2 sleep (the major class in terms of classification) to bring down errors in other sleep stages. Moreover the network becomes much more robust, meaning that for all subjects where the baseline method had exceptionally poor performance, their performance are improved significantly. Finally, the computation time only grows at a sub-linear rate when the sequence length increases.

Original languageEnglish
JournalIEEE Journal of Biomedical and Health Informatics
Volume27
Issue10
Pages (from-to)4748-4757
Number of pages10
ISSN2168-2194
DOIs
Publication statusPublished - Oct 2023

Keywords

  • Automatic sleep staging
  • deep neural network
  • long sequence modelling
  • sequence-to-sequence

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