Investigating the causal relationship between neuroticism and depression via Mendelian Randomization

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperLetterpeer-review

Standard

Investigating the causal relationship between neuroticism and depression via Mendelian Randomization. / Speed, Doug; Hemani, Gibran; Speed, Maria S; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium ; Børglum, Anders D.

In: Acta Psychiatrica Scandinavica, Vol. 139, No. 4, 2019, p. 395-397.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperLetterpeer-review

Harvard

Speed, D, Hemani, G, Speed, MS, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & Børglum, AD 2019, 'Investigating the causal relationship between neuroticism and depression via Mendelian Randomization', Acta Psychiatrica Scandinavica, vol. 139, no. 4, pp. 395-397. https://doi.org/10.1111/acps.13009

APA

Speed, D., Hemani, G., Speed, M. S., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, & Børglum, A. D. (2019). Investigating the causal relationship between neuroticism and depression via Mendelian Randomization. Acta Psychiatrica Scandinavica, 139(4), 395-397. https://doi.org/10.1111/acps.13009

CBE

Speed D, Hemani G, Speed MS, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Børglum AD. 2019. Investigating the causal relationship between neuroticism and depression via Mendelian Randomization. Acta Psychiatrica Scandinavica. 139(4):395-397. https://doi.org/10.1111/acps.13009

MLA

Vancouver

Speed D, Hemani G, Speed MS, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Børglum AD. Investigating the causal relationship between neuroticism and depression via Mendelian Randomization. Acta Psychiatrica Scandinavica. 2019;139(4):395-397. https://doi.org/10.1111/acps.13009

Author

Speed, Doug ; Hemani, Gibran ; Speed, Maria S ; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium ; Børglum, Anders D. / Investigating the causal relationship between neuroticism and depression via Mendelian Randomization. In: Acta Psychiatrica Scandinavica. 2019 ; Vol. 139, No. 4. pp. 395-397.

Bibtex

@article{2a4e64a9925d4e88a625b5a5f012036f,
title = "Investigating the causal relationship between neuroticism and depression via Mendelian Randomization",
abstract = "Neuroticism is a heritable personality trait, characterized by negative emotions such as worrying, feelings of guilt, loneliness and being easily hurt. Increased levels of neuroticism are associated with poor mental health - development of depression in particular - but it remains uncertain whether this association represents a causal effect [1]. Here, we use Mendelian randomization (MR) to investigate whether neuroticism is a causal risk factor for development of depression. This article is protected by copyright. All rights reserved.",
author = "Doug Speed and Gibran Hemani and Speed, {Maria S} and {Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium} and B{\o}rglum, {Anders D} and {\O}stergaard, {S{\o}ren D} and Christensen, {Jane Hvarregaard} and Buttensch{\o}n, {Henriette N{\o}rm{\o}lle} and Mortensen, {Preben Bo} and Jakob Grove and Per Qvist",
note = "This article is protected by copyright. All rights reserved.",
year = "2019",
doi = "10.1111/acps.13009",
language = "English",
volume = "139",
pages = "395--397",
journal = "Acta Psychiatrica Scandinavica",
issn = "0001-690X",
publisher = "Jossey-Bass",
number = "4",

}

RIS

TY - JOUR

T1 - Investigating the causal relationship between neuroticism and depression via Mendelian Randomization

AU - Speed, Doug

AU - Hemani, Gibran

AU - Speed, Maria S

AU - Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

AU - Børglum, Anders D

AU - Østergaard, Søren D

AU - Christensen, Jane Hvarregaard

AU - Buttenschøn, Henriette Nørmølle

AU - Mortensen, Preben Bo

AU - Grove, Jakob

AU - Qvist, Per

N1 - This article is protected by copyright. All rights reserved.

PY - 2019

Y1 - 2019

N2 - Neuroticism is a heritable personality trait, characterized by negative emotions such as worrying, feelings of guilt, loneliness and being easily hurt. Increased levels of neuroticism are associated with poor mental health - development of depression in particular - but it remains uncertain whether this association represents a causal effect [1]. Here, we use Mendelian randomization (MR) to investigate whether neuroticism is a causal risk factor for development of depression. This article is protected by copyright. All rights reserved.

AB - Neuroticism is a heritable personality trait, characterized by negative emotions such as worrying, feelings of guilt, loneliness and being easily hurt. Increased levels of neuroticism are associated with poor mental health - development of depression in particular - but it remains uncertain whether this association represents a causal effect [1]. Here, we use Mendelian randomization (MR) to investigate whether neuroticism is a causal risk factor for development of depression. This article is protected by copyright. All rights reserved.

UR - http://www.scopus.com/inward/record.url?scp=85061836520&partnerID=8YFLogxK

U2 - 10.1111/acps.13009

DO - 10.1111/acps.13009

M3 - Letter

C2 - 30697695

VL - 139

SP - 395

EP - 397

JO - Acta Psychiatrica Scandinavica

JF - Acta Psychiatrica Scandinavica

SN - 0001-690X

IS - 4

ER -