Inter-species transmission of viral hamoerrhagic septicaemia virus (VHSV) from turbot (Scophtalmus maximus) to rainbow trout (Onchorhyncus mykiss)

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  • Anna Schönherz
  • Niels Lorenzen, Technical University of Denmark, Denmark
  • Katja Einer-Jensen, Division of Poultry, Fish and Fur Animals, Denmark
Successful viral infection is a complex mechanism, involving many host-pathogen interactions that developed during coevolution of host and pathogen, and often result in host-species specificity. Nevertheless, many viruses are able to infect several host species and sporadically cross species barriers. The viral haemorrhagic septicaemia virus (VHSV), a rhabdovirus with high economic impact on aquaculture industry, has developed an exceptional wide host range across marine- and freshwater environments. Transmission of VHSV between host species therefore represents a potential risk for aquaculture, which is not addressed in biosecurity managements currently. The objective of this study was to investigate the inter-species transmission potential of VHSV and evaluate whether infected marine wild fish pose a potential risk on marine cultured rainbow trout. A cohabitation infection trial with turbot as donor- and rainbow trout as recipient host species was conducted. Turbot were intraperitoneally (i.p.) injected with either a marine adapted- (MA) or a trout adapted (TA) VHSV isolate and subsequently grouped with naïve rainbow trout. Both VHSV isolates were able to replicate and cause mortality in turbot, while only the TA isolate was able to cross the species barrier and infect rainbow trout with fatal outcome. The results demonstrate that a marine fish species can function as reservoir and transmitter of trout adapted VHSV isolates.
Original languageEnglish
JournalJournal of General Virology
Volume94
Issue4
Pages (from-to)869-875
Number of pages7
ISSN0022-1317
DOIs
Publication statusPublished - Apr 2013

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