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Interaction of pH-responsive polyanions with phospholipid membranes

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DOI

  • Edit Brodszkij
  • ,
  • Martin J. Hviid
  • ,
  • Carina Ade
  • ,
  • Philipp S. Schattling
  • ,
  • Moritz Burmeister
  • ,
  • Sven Szilagyi
  • ,
  • Noga Gal
  • ,
  • Chuntao Zhu, Harbin Institute of Technology
  • ,
  • Xiaojun Han, Harbin Institute of Technology
  • ,
  • Brigitte Städler

The behavior of two acrylate polymers, with carboxylic acid side groups, was investigated with regard to their pH-responsive interaction with phospholipid membranes. The polyanions crossed the membrane of giant unilamellar vesicles and mammalian cells with low cytotoxicity in the latter case.

Original languageEnglish
JournalPolymer Chemistry
Volume10
Issue44
Pages (from-to)5992-5997
Number of pages6
ISSN1759-9954
DOIs
Publication statusPublished - Nov 2019

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