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Influence of Family Structure on Variance Decomposition

Research output: Contribution to conferencePosterResearch

  • Stefan McKinnon Edwards, Denmark
  • Pernille Merete Sarup, Denmark
  • Peter Sørensen
Partitioning genetic variance by sets of randomly sampled genes for complex traits in D. melanogaster and B. taurus, has revealed that population structure can affect variance decomposition. In fruit flies, we found that a high likelihood ratio is correlated with a high proportion of explained genetic variance. However, in Holstein cattle, a group of genes that explained close to none of the genetic variance could also have a high likelihood ratio. This is still a good separation of signal and noise, but instead of capturing the genetic signal in the marker set being tested, we are instead capturing pure noise. Therefore it is necessary to use both criteria, high likelihood ratio in favor of a more complex genetic model and proportion of genetic variance explained, to identify biologically important gene groups
Original languageEnglish
Publication year18 Aug 2014
Number of pages1
Publication statusPublished - 18 Aug 2014
Event10th World Congress on Genetics Applied to Livestock Production (WCGALP) - The Westin Bayshore, 1601 Bayshore Drive, Vancouver, BC V6G 2V4, Vancouver, Canada
Duration: 17 Aug 201422 Aug 2014
Conference number: 10th

Conference

Conference10th World Congress on Genetics Applied to Livestock Production (WCGALP)
Number10th
LocationThe Westin Bayshore, 1601 Bayshore Drive, Vancouver, BC V6G 2V4
CountryCanada
CityVancouver
Period17/08/201422/08/2014

    Research areas

  • Linear mixed models, Holstein dairy cattle, Fruit flies

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