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In vivo imaging of cerebral serotonin transporter and serotonin(2A) receptor binding in 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") and hallucinogen users

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • David Erritzoe
  • ,
  • Vibe G Frokjaer
  • ,
  • Klaus K Holst
  • ,
  • Maria Christoffersen
  • ,
  • Sys S Johansen
  • ,
  • Claus Svarer
  • ,
  • Jacob Madsen
  • ,
  • Peter Mondrup Rasmussen
  • Thomas Ramsøy
  • ,
  • Terry L Jernigan
  • ,
  • Gitte M Knudsen
Both hallucinogens and 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") have direct agonistic effects on postsynaptic serotonin(2A) receptors, the key site for hallucinogenic actions. In addition, MDMA is a potent releaser and reuptake inhibitor of presynaptic serotonin.
Original languageEnglish
JournalArchives of general psychiatry
Volume68
Issue6
Pages (from-to)562-76
Number of pages15
ISSN0003-990X
DOIs
Publication statusPublished - 2011
Externally publishedYes

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