In vitro and in silico assessment of the developability of a designed monoclonal antibody library

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • Adriana-Michelle Wolf Pérez
  • Pietro Sormanni, h Modelling Department , Novo Nordisk A/S , Måløv , Denmark.
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  • Jonathan Sonne Andersen, h Modelling Department , Novo Nordisk A/S , Måløv , Denmark.
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  • Laila Ismail Sakhnini, h Modelling Department , Novo Nordisk A/S , Måløv , Denmark.
  • ,
  • Ileana Rodriguez-Leon, h Modelling Department , Novo Nordisk A/S , Måløv , Denmark.
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  • Jais Rose Bjelke, h Modelling Department , Novo Nordisk A/S , Måløv , Denmark.
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  • Annette Juhl Gajhede, h Modelling Department , Novo Nordisk A/S , Måløv , Denmark.
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  • Leonardo De Maria, h Modelling Department , Novo Nordisk A/S , Måløv , Denmark.
  • ,
  • Daniel E Otzen
  • Michele Vendruscolo, h Modelling Department , Novo Nordisk A/S , Måløv , Denmark.
  • ,
  • Nikolai Lorenzen, Novo Nordisk
Original languageEnglish
JournalmAbs
Volume11
Issue2
Pages (from-to)388-400
Number of pages13
ISSN1942-0862
DOIs
Publication statusPublished - 2019

    Research areas

  • DISCOVERY, PREDICTION, PROTEIN AGGREGATION, RATIONAL DESIGN, SELF-ASSOCIATION, SEQUENCE, SOLUBILITY, STABILITY, THERAPEUTIC ANTIBODIES, VISCOSITY, biophysical properties, computational predictions, developability assessment, monoclonal antibodies

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