Hepatosplenic schistosomiasis: playing hide-and-seek with an elusive parasite

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Hepatosplenic schistosomiasis : playing hide-and-seek with an elusive parasite. / Baekby, Martin; Glerup, Henning; Stribolt, Katrine et al.

In: B M J Case Reports, Vol. 2017, 16.08.2017.

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@article{098a4107d3c4463889ee973bafa13291,
title = "Hepatosplenic schistosomiasis: playing hide-and-seek with an elusive parasite",
abstract = "A 27-year-old man of Eritrean origin presented with persistent left-sided abdominal pain. Initial investigation showed signs of liver fibrosis, portal hypertension and splenomegaly. A diagnosis of hepatosplenic schistosomiasis was suspected on grounds of elevated total IgE, grey area antischistosomiasis antibodies and the high endemic status of his native country. However, repeated microscopy of faecal and urine samples, as well as rectal biopsies, failed to demonstrate schistosomal eggs. Finally, the diagnosis of hepatosplenic schistosomiasis was established through demonstration of a Schistosoma mansoni egg in a liver biopsy taken in an attempt to clarify the cause of the above findings. The patient had recently been treated for uncomplicated malaria. Lowered schistosomiasis worm/egg burden and hence reduced sensitivity of classic microscopy-based schistosomiasis testing was attributed to the antischistosomal activity of the antimalarial chemotherapy.",
keywords = "Journal Article",
author = "Martin Baekby and Henning Glerup and Katrine Stribolt and Britta Tarp",
note = "{\textcopyright} BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.",
year = "2017",
month = aug,
day = "16",
doi = "10.1136/bcr-2017-219437",
language = "English",
volume = "2017",
journal = "B M J Case Reports",
issn = "1757-790X",
publisher = "BMJ Publishing Group",

}

RIS

TY - JOUR

T1 - Hepatosplenic schistosomiasis

T2 - playing hide-and-seek with an elusive parasite

AU - Baekby, Martin

AU - Glerup, Henning

AU - Stribolt, Katrine

AU - Tarp, Britta

N1 - © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

PY - 2017/8/16

Y1 - 2017/8/16

N2 - A 27-year-old man of Eritrean origin presented with persistent left-sided abdominal pain. Initial investigation showed signs of liver fibrosis, portal hypertension and splenomegaly. A diagnosis of hepatosplenic schistosomiasis was suspected on grounds of elevated total IgE, grey area antischistosomiasis antibodies and the high endemic status of his native country. However, repeated microscopy of faecal and urine samples, as well as rectal biopsies, failed to demonstrate schistosomal eggs. Finally, the diagnosis of hepatosplenic schistosomiasis was established through demonstration of a Schistosoma mansoni egg in a liver biopsy taken in an attempt to clarify the cause of the above findings. The patient had recently been treated for uncomplicated malaria. Lowered schistosomiasis worm/egg burden and hence reduced sensitivity of classic microscopy-based schistosomiasis testing was attributed to the antischistosomal activity of the antimalarial chemotherapy.

AB - A 27-year-old man of Eritrean origin presented with persistent left-sided abdominal pain. Initial investigation showed signs of liver fibrosis, portal hypertension and splenomegaly. A diagnosis of hepatosplenic schistosomiasis was suspected on grounds of elevated total IgE, grey area antischistosomiasis antibodies and the high endemic status of his native country. However, repeated microscopy of faecal and urine samples, as well as rectal biopsies, failed to demonstrate schistosomal eggs. Finally, the diagnosis of hepatosplenic schistosomiasis was established through demonstration of a Schistosoma mansoni egg in a liver biopsy taken in an attempt to clarify the cause of the above findings. The patient had recently been treated for uncomplicated malaria. Lowered schistosomiasis worm/egg burden and hence reduced sensitivity of classic microscopy-based schistosomiasis testing was attributed to the antischistosomal activity of the antimalarial chemotherapy.

KW - Journal Article

U2 - 10.1136/bcr-2017-219437

DO - 10.1136/bcr-2017-219437

M3 - Journal article

C2 - 28814579

VL - 2017

JO - B M J Case Reports

JF - B M J Case Reports

SN - 1757-790X

ER -