Halve the dose while maintaining image quality in paediatric Cone Beam CT

DIMITRA Research Group

doi:10.1038/s41598-019-41949-w

Halve the dose while maintaining image quality in paediatric Cone Beam CT

DIMITRA Research Group

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Abstract

Cone beam CT (CBCT) for dentomaxillofacial paediatric assessment has been widely used despite the uncertainties of the risks of the low-dose radiation exposures. The aim of this work was to investigate the clinical performance of different CBCT acquisition protocols towards the optimization of paediatric exposures. Custom-made anthropomorphic phantoms were scanned using a CBCT unit in six protocols. CT slices were blinded, randomized and presented to three observers, who scored the image quality using a 4-point scale along with their level of confidence. Sharpness level was also measured using a test object containing an air/PMMA e,dge. The effective dose was calculated by means of a customized Monte Carlo (MC) framework using previously validated paediatric voxels models. The results have shown that the protocols set with smaller voxel size (180 µm), even when decreasing exposure parameters (kVp and mAs), showed high image quality scores and increased sharpness. The MC analysis showed a gradual decrease in effective dose when exposures parameters were reduced, with an emphasis on an average reduction of 45% for the protocol that combined 70 kVp, 16 mAs and 180 µm voxel size. In contrast, both “ultra-low dose” protocols that combined a larger voxel size (400 µm) with lower mAs (7.4 mAs) demonstrated the lowest scores with high levels of confidence unsuitable for an anatomical approach. In conclusion, a significant decrease in the effective dose can be achieved while maintaining the image quality required for paediatric CBCT.

Original language	English
Article number	5521
Journal	Scientific Reports
Volume	9
Issue	1
ISSN	2045-2322
DOIs	https://doi.org/10.1038/s41598-019-41949-w
Publication status	Published - 1 Dec 2019
Externally published	Yes

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10.1038/s41598-019-41949-w

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@article{ece6cf25b7d544908efcfd84a432ea2a,

title = "Halve the dose while maintaining image quality in paediatric Cone Beam CT",

abstract = "Cone beam CT (CBCT) for dentomaxillofacial paediatric assessment has been widely used despite the uncertainties of the risks of the low-dose radiation exposures. The aim of this work was to investigate the clinical performance of different CBCT acquisition protocols towards the optimization of paediatric exposures. Custom-made anthropomorphic phantoms were scanned using a CBCT unit in six protocols. CT slices were blinded, randomized and presented to three observers, who scored the image quality using a 4-point scale along with their level of confidence. Sharpness level was also measured using a test object containing an air/PMMA e,dge. The effective dose was calculated by means of a customized Monte Carlo (MC) framework using previously validated paediatric voxels models. The results have shown that the protocols set with smaller voxel size (180 µm), even when decreasing exposure parameters (kVp and mAs), showed high image quality scores and increased sharpness. The MC analysis showed a gradual decrease in effective dose when exposures parameters were reduced, with an emphasis on an average reduction of 45% for the protocol that combined 70 kVp, 16 mAs and 180 µm voxel size. In contrast, both “ultra-low dose” protocols that combined a larger voxel size (400 µm) with lower mAs (7.4 mAs) demonstrated the lowest scores with high levels of confidence unsuitable for an anatomical approach. In conclusion, a significant decrease in the effective dose can be achieved while maintaining the image quality required for paediatric CBCT.",

author = "Oenning, {Anne Caroline} and Ruben Pauwels and Andreas Stratis and {De Faria Vasconcelos}, Karla and Elisabeth Tijskens and {De Grauwe}, Annelore and Reinhilde Jacobs and Benjamin Salmon and Catherine Chaussain and Hilde Bosmans and Ria Bogaerts and Constantinus Politis and Laura Nicolielo and Guozhi Zhang and Myrthel Vranckx and Anna Ockerman and Sarah Baatout and Niels Belmans and Marjan Moreels and Mihaela Hedesiu and Pirsoka Virag and Mihaela Baciut and Maria Marcu and Oana Almasan and Raluca Roman and Ioan Barbur and Cristian Dinu and Horatiu Rotaru and Lucia Hurubeanu and Vlad Istouan and Ondine Lucaciu and Daniel Leucuta and Bogdan Crisan and Loredana Bogdan and Ciprian Candea and Simion Bran and Grigore Baciut and {DIMITRA Research Group}",

note = "Funding Information: This research has received funding from the European Atomic Energy Community{\textquoteright}s Seventh Framework Programme FP7/2007–2011 Under Grant Agreement No. 604984 (OPERRA: Open Project for the European Radiation Research Area). The authors would like to thank Bryan Mac Kay for his proofreading of the English. Publisher Copyright: {\textcopyright} 2019, The Author(s).",

year = "2019",

month = dec,

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doi = "10.1038/s41598-019-41949-w",

language = "English",

volume = "9",

journal = "Scientific Reports",

issn = "2045-2322",

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T1 - Halve the dose while maintaining image quality in paediatric Cone Beam CT

AU - Oenning, Anne Caroline

AU - Pauwels, Ruben

AU - Stratis, Andreas

AU - De Faria Vasconcelos, Karla

AU - Tijskens, Elisabeth

AU - De Grauwe, Annelore

AU - Jacobs, Reinhilde

AU - Salmon, Benjamin

AU - Chaussain, Catherine

AU - Bosmans, Hilde

AU - Bogaerts, Ria

AU - Politis, Constantinus

AU - Nicolielo, Laura

AU - Zhang, Guozhi

AU - Vranckx, Myrthel

AU - Ockerman, Anna

AU - Baatout, Sarah

AU - Belmans, Niels

AU - Moreels, Marjan

AU - Hedesiu, Mihaela

AU - Virag, Pirsoka

AU - Baciut, Mihaela

AU - Marcu, Maria

AU - Almasan, Oana

AU - Roman, Raluca

AU - Barbur, Ioan

AU - Dinu, Cristian

AU - Rotaru, Horatiu

AU - Hurubeanu, Lucia

AU - Istouan, Vlad

AU - Lucaciu, Ondine

AU - Leucuta, Daniel

AU - Crisan, Bogdan

AU - Bogdan, Loredana

AU - Candea, Ciprian

AU - Bran, Simion

AU - Baciut, Grigore

AU - DIMITRA Research Group

N1 - Funding Information: This research has received funding from the European Atomic Energy Community’s Seventh Framework Programme FP7/2007–2011 Under Grant Agreement No. 604984 (OPERRA: Open Project for the European Radiation Research Area). The authors would like to thank Bryan Mac Kay for his proofreading of the English. Publisher Copyright: © 2019, The Author(s).

PY - 2019/12/1

Y1 - 2019/12/1

N2 - Cone beam CT (CBCT) for dentomaxillofacial paediatric assessment has been widely used despite the uncertainties of the risks of the low-dose radiation exposures. The aim of this work was to investigate the clinical performance of different CBCT acquisition protocols towards the optimization of paediatric exposures. Custom-made anthropomorphic phantoms were scanned using a CBCT unit in six protocols. CT slices were blinded, randomized and presented to three observers, who scored the image quality using a 4-point scale along with their level of confidence. Sharpness level was also measured using a test object containing an air/PMMA e,dge. The effective dose was calculated by means of a customized Monte Carlo (MC) framework using previously validated paediatric voxels models. The results have shown that the protocols set with smaller voxel size (180 µm), even when decreasing exposure parameters (kVp and mAs), showed high image quality scores and increased sharpness. The MC analysis showed a gradual decrease in effective dose when exposures parameters were reduced, with an emphasis on an average reduction of 45% for the protocol that combined 70 kVp, 16 mAs and 180 µm voxel size. In contrast, both “ultra-low dose” protocols that combined a larger voxel size (400 µm) with lower mAs (7.4 mAs) demonstrated the lowest scores with high levels of confidence unsuitable for an anatomical approach. In conclusion, a significant decrease in the effective dose can be achieved while maintaining the image quality required for paediatric CBCT.

AB - Cone beam CT (CBCT) for dentomaxillofacial paediatric assessment has been widely used despite the uncertainties of the risks of the low-dose radiation exposures. The aim of this work was to investigate the clinical performance of different CBCT acquisition protocols towards the optimization of paediatric exposures. Custom-made anthropomorphic phantoms were scanned using a CBCT unit in six protocols. CT slices were blinded, randomized and presented to three observers, who scored the image quality using a 4-point scale along with their level of confidence. Sharpness level was also measured using a test object containing an air/PMMA e,dge. The effective dose was calculated by means of a customized Monte Carlo (MC) framework using previously validated paediatric voxels models. The results have shown that the protocols set with smaller voxel size (180 µm), even when decreasing exposure parameters (kVp and mAs), showed high image quality scores and increased sharpness. The MC analysis showed a gradual decrease in effective dose when exposures parameters were reduced, with an emphasis on an average reduction of 45% for the protocol that combined 70 kVp, 16 mAs and 180 µm voxel size. In contrast, both “ultra-low dose” protocols that combined a larger voxel size (400 µm) with lower mAs (7.4 mAs) demonstrated the lowest scores with high levels of confidence unsuitable for an anatomical approach. In conclusion, a significant decrease in the effective dose can be achieved while maintaining the image quality required for paediatric CBCT.

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U2 - 10.1038/s41598-019-41949-w

DO - 10.1038/s41598-019-41949-w

M3 - Journal article

C2 - 30940872

AN - SCOPUS:85063755952

SN - 2045-2322

VL - 9

JO - Scientific Reports

JF - Scientific Reports

IS - 1

M1 - 5521

ER -

Halve the dose while maintaining image quality in paediatric Cone Beam CT

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