Genotyping dead animals improves post-weaning survival of pigs in breeding programs

TY - GEN

T1 - Genotyping dead animals improves post-weaning survival of pigs in breeding programs

AU - Islam, Md Shariful

AU - Van der Werf, JHJ

AU - Henryon, Mark

AU - Chu, Thinh Tuan

AU - Wood, B. J.

AU - Hermesch, S

N1 - Conference code: 12

PY - 2022

Y1 - 2022

N2 - A premise was tested that genotyping both surviving and dead pigs will realise more genetic gain in post-weaning survival (PWS) than genotyping only surviving animals. Stochastic simulation was used to estimate the rate of true genetic gain in different genotyping scenarios that differed in varying proportions of genotyping dead animals. Selection was for only PWS that had heritability of 0.02. Mortality was assumed 10%. The trait was controlled by 7,702 biallelic quantitative trait loci distributed across a 30 Morgan genome. We used 54,218 biallelic single nucleotide polymorphisms (SNPs) that were used in genomic prediction. Genotyping both surviving and dead animals realised 12 to 24% more genetic gain than genotyping only surviving animals. The power of detecting SNP effects increased when animals of extreme phenotypes are genotyped. Therefore, genotyping both surviving and dead pigs realised more genetic gain than genotyping only surviving animals

AB - A premise was tested that genotyping both surviving and dead pigs will realise more genetic gain in post-weaning survival (PWS) than genotyping only surviving animals. Stochastic simulation was used to estimate the rate of true genetic gain in different genotyping scenarios that differed in varying proportions of genotyping dead animals. Selection was for only PWS that had heritability of 0.02. Mortality was assumed 10%. The trait was controlled by 7,702 biallelic quantitative trait loci distributed across a 30 Morgan genome. We used 54,218 biallelic single nucleotide polymorphisms (SNPs) that were used in genomic prediction. Genotyping both surviving and dead animals realised 12 to 24% more genetic gain than genotyping only surviving animals. The power of detecting SNP effects increased when animals of extreme phenotypes are genotyped. Therefore, genotyping both surviving and dead pigs realised more genetic gain than genotyping only surviving animals

M3 - Article in proceedings

BT - WCGALP2022 Programme book

PB - Wageningen Academic Publishers

T2 - World Congress on Genetics Applied to Livestock Production

Y2 - 3 July 2022 through 8 July 2022

ER -