TY - JOUR
T1 - Genetic analysis of global faba bean diversity, agronomic traits and selection signatures
AU - Skovbjerg, Cathrine Kiel
AU - Angra, Deepti
AU - Robertson-Shersby-Harvie, Tom
AU - Kreplak, Jonathan
AU - Keeble-Gagnère, Gabriel
AU - Kaur, Sukhjiwan
AU - Ecke, Wolfgang
AU - Windhorst, Alex
AU - Nielsen, Linda Kærgaard
AU - Schiemann, Andrea
AU - Knudsen, Jens
AU - Gutierrez, Natalia
AU - Tagkouli, Vasiliki
AU - Fechete, Lavinia Ioana
AU - Janss, Luc
AU - Stougaard, Jens
AU - Warsame, Ahmed
AU - Alves, Sheila
AU - Khazaei, Hamid
AU - Link, Wolfgang
AU - Torres, Ana Maria
AU - O'Sullivan, Donal Martin
AU - Andersen, Stig Uggerhøj
PY - 2023/5
Y1 - 2023/5
N2 - Key message: We identified marker-trait associations for key faba bean agronomic traits and genomic signatures of selection within a global germplasm collection. Abstract: Faba bean (Vicia faba L.) is a high-protein grain legume crop with great potential for sustainable protein production. However, little is known about the genetics underlying trait diversity. In this study, we used 21,345 high-quality SNP markers to genetically characterize 2678 faba bean genotypes. We performed genome-wide association studies of key agronomic traits using a seven-parent-MAGIC population and detected 238 significant marker-trait associations linked to 12 traits of agronomic importance. Sixty-five of these were stable across multiple environments. Using a non-redundant diversity panel of 685 accessions from 52 countries, we identified three subpopulations differentiated by geographical origin and 33 genomic regions subjected to strong diversifying selection between subpopulations. We found that SNP markers associated with the differentiation of northern and southern accessions explained a significant proportion of agronomic trait variance in the seven-parent-MAGIC population, suggesting that some of these traits were targets of selection during breeding. Our findings point to genomic regions associated with important agronomic traits and selection, facilitating faba bean genomics-based breeding.
AB - Key message: We identified marker-trait associations for key faba bean agronomic traits and genomic signatures of selection within a global germplasm collection. Abstract: Faba bean (Vicia faba L.) is a high-protein grain legume crop with great potential for sustainable protein production. However, little is known about the genetics underlying trait diversity. In this study, we used 21,345 high-quality SNP markers to genetically characterize 2678 faba bean genotypes. We performed genome-wide association studies of key agronomic traits using a seven-parent-MAGIC population and detected 238 significant marker-trait associations linked to 12 traits of agronomic importance. Sixty-five of these were stable across multiple environments. Using a non-redundant diversity panel of 685 accessions from 52 countries, we identified three subpopulations differentiated by geographical origin and 33 genomic regions subjected to strong diversifying selection between subpopulations. We found that SNP markers associated with the differentiation of northern and southern accessions explained a significant proportion of agronomic trait variance in the seven-parent-MAGIC population, suggesting that some of these traits were targets of selection during breeding. Our findings point to genomic regions associated with important agronomic traits and selection, facilitating faba bean genomics-based breeding.
UR - http://www.scopus.com/inward/record.url?scp=85153122639&partnerID=8YFLogxK
U2 - 10.1007/s00122-023-04360-8
DO - 10.1007/s00122-023-04360-8
M3 - Journal article
C2 - 37074596
SN - 0040-5752
VL - 136
JO - Theoretical and Applied Genetics
JF - Theoretical and Applied Genetics
IS - 5
M1 - 114
ER -