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Gastrointestinal motility during sleep assessed by tracking of telemetric capsules combined with polysomnography - a pilot study

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Gastrointestinal motility during sleep assessed by tracking of telemetric capsules combined with polysomnography - a pilot study. / Haase, Anne-Mette; Fallet, Sibylle; Otto, Marit; Scott, S Mark; Schlageter, Vincent; Krogh, Klaus.

In: Clinical and Experimental Gastroenterology, Vol. 8, 12.2015, p. 327-32.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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Haase, Anne-Mette ; Fallet, Sibylle ; Otto, Marit ; Scott, S Mark ; Schlageter, Vincent ; Krogh, Klaus. / Gastrointestinal motility during sleep assessed by tracking of telemetric capsules combined with polysomnography - a pilot study. In: Clinical and Experimental Gastroenterology. 2015 ; Vol. 8. pp. 327-32.

Bibtex

@article{1cff158fce4742b28e1392f7f79fd080,
title = "Gastrointestinal motility during sleep assessed by tracking of telemetric capsules combined with polysomnography - a pilot study",
abstract = "Studies of gastrointestinal function during sleep are hampered by lack of applicable techniques. Recent development of a novel ambulatory telemetric capsule system, which can be used in conjunction with polysomnography, offers a solution to this problem. The 3D-Transit system consists of ingestible electromagnetic capsules traceable through a portable extracorporeal receiver while traversing the gut. During sleep monitored by polysomnography, gastrointestinal motility was concurrently investigated using 3D-Transit in nine healthy subjects. Overall, the amplitude of gastric contractions decreased with depth of sleep (light sleep, N2 versus deep sleep, N3; P<0.05). Progression through the small intestine did not change with depth of sleep (Kruskal-Wallis probability =0.1), and there was no association between nocturnal awakenings or arousals and the occurrence of colonic or small intestinal propagating movements. Basal colonic activity was suppressed during both deep sleep (P<0.05) and light sleep (P<0.05) when compared with nocturnal wake periods. In conclusion, the novel ambulatory 3D-Transit system combined with polysomnography allows minimally invasive and completely ambulatory investigation of associations between sleep patterns and gastrointestinal motility.",
author = "Anne-Mette Haase and Sibylle Fallet and Marit Otto and Scott, {S Mark} and Vincent Schlageter and Klaus Krogh",
year = "2015",
month = dec,
doi = "10.2147/CEG.S91964",
language = "English",
volume = "8",
pages = "327--32",
journal = "Clinical and Experimental Gastroenterology",
issn = "1178-7023",
publisher = "Dove Medical Press Ltd.(Dovepress)",

}

RIS

TY - JOUR

T1 - Gastrointestinal motility during sleep assessed by tracking of telemetric capsules combined with polysomnography - a pilot study

AU - Haase, Anne-Mette

AU - Fallet, Sibylle

AU - Otto, Marit

AU - Scott, S Mark

AU - Schlageter, Vincent

AU - Krogh, Klaus

PY - 2015/12

Y1 - 2015/12

N2 - Studies of gastrointestinal function during sleep are hampered by lack of applicable techniques. Recent development of a novel ambulatory telemetric capsule system, which can be used in conjunction with polysomnography, offers a solution to this problem. The 3D-Transit system consists of ingestible electromagnetic capsules traceable through a portable extracorporeal receiver while traversing the gut. During sleep monitored by polysomnography, gastrointestinal motility was concurrently investigated using 3D-Transit in nine healthy subjects. Overall, the amplitude of gastric contractions decreased with depth of sleep (light sleep, N2 versus deep sleep, N3; P<0.05). Progression through the small intestine did not change with depth of sleep (Kruskal-Wallis probability =0.1), and there was no association between nocturnal awakenings or arousals and the occurrence of colonic or small intestinal propagating movements. Basal colonic activity was suppressed during both deep sleep (P<0.05) and light sleep (P<0.05) when compared with nocturnal wake periods. In conclusion, the novel ambulatory 3D-Transit system combined with polysomnography allows minimally invasive and completely ambulatory investigation of associations between sleep patterns and gastrointestinal motility.

AB - Studies of gastrointestinal function during sleep are hampered by lack of applicable techniques. Recent development of a novel ambulatory telemetric capsule system, which can be used in conjunction with polysomnography, offers a solution to this problem. The 3D-Transit system consists of ingestible electromagnetic capsules traceable through a portable extracorporeal receiver while traversing the gut. During sleep monitored by polysomnography, gastrointestinal motility was concurrently investigated using 3D-Transit in nine healthy subjects. Overall, the amplitude of gastric contractions decreased with depth of sleep (light sleep, N2 versus deep sleep, N3; P<0.05). Progression through the small intestine did not change with depth of sleep (Kruskal-Wallis probability =0.1), and there was no association between nocturnal awakenings or arousals and the occurrence of colonic or small intestinal propagating movements. Basal colonic activity was suppressed during both deep sleep (P<0.05) and light sleep (P<0.05) when compared with nocturnal wake periods. In conclusion, the novel ambulatory 3D-Transit system combined with polysomnography allows minimally invasive and completely ambulatory investigation of associations between sleep patterns and gastrointestinal motility.

U2 - 10.2147/CEG.S91964

DO - 10.2147/CEG.S91964

M3 - Journal article

C2 - 26677340

VL - 8

SP - 327

EP - 332

JO - Clinical and Experimental Gastroenterology

JF - Clinical and Experimental Gastroenterology

SN - 1178-7023

ER -