Fungal keratitis - improving diagnostics by confocal microscopy

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Fungal keratitis - improving diagnostics by confocal microscopy. / Nielsen, Esben; Heegaard, S; Prause, J U; Ivarsen, A; Mortensen, K L; Hjortdal, J.

In: Case Reports in Ophthalmology, Vol. 4, No. 3, 09.2013, p. 303-10.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

Harvard

Nielsen, E, Heegaard, S, Prause, JU, Ivarsen, A, Mortensen, KL & Hjortdal, J 2013, 'Fungal keratitis - improving diagnostics by confocal microscopy', Case Reports in Ophthalmology, vol. 4, no. 3, pp. 303-10. https://doi.org/10.1159/000357558

APA

Nielsen, E., Heegaard, S., Prause, J. U., Ivarsen, A., Mortensen, K. L., & Hjortdal, J. (2013). Fungal keratitis - improving diagnostics by confocal microscopy. Case Reports in Ophthalmology, 4(3), 303-10. https://doi.org/10.1159/000357558

CBE

MLA

Nielsen, Esben et al. "Fungal keratitis - improving diagnostics by confocal microscopy". Case Reports in Ophthalmology. 2013, 4(3). 303-10. https://doi.org/10.1159/000357558

Vancouver

Nielsen E, Heegaard S, Prause JU, Ivarsen A, Mortensen KL, Hjortdal J. Fungal keratitis - improving diagnostics by confocal microscopy. Case Reports in Ophthalmology. 2013 Sep;4(3):303-10. https://doi.org/10.1159/000357558

Author

Nielsen, Esben ; Heegaard, S ; Prause, J U ; Ivarsen, A ; Mortensen, K L ; Hjortdal, J. / Fungal keratitis - improving diagnostics by confocal microscopy. In: Case Reports in Ophthalmology. 2013 ; Vol. 4, No. 3. pp. 303-10.

Bibtex

@article{d87e18c65bc746b986d4514aeceeba19,
title = "Fungal keratitis - improving diagnostics by confocal microscopy",
abstract = "Purpose: Introducing a simple image grading system to support the interpretation of in vivo confocal microscopy (IVCM) images in filamentous fungal keratitis. Setting: Clinical and confocal studies took place at the Department of Ophthalmology, Aarhus University Hospital, Denmark. Histopathological analysis was performed at the Eye Pathology Institute, Department of Neuroscience and Pharmacology, University of Copenhagen, Denmark. Methods: A recent series of consecutive patients with filamentous fungal keratitis is presented to demonstrate the results from in-house IVCM. Based upon our experience with IVCM and previously published images, we composed a grading system for interpreting IVCM images of filamentous fungal keratitis. Results: A recent case series of filamentous fungal keratitis from 2011 to 2012 was examined. There were 3 male and 3 female patients. Mean age was 44.5 years (range 12-69), 6 out of 17 (35{\%}) cultures were positive and a total of 6/7 (86{\%}) IVCM scans were positive. Three different categories of IVCM results for the grading of diagnostic certainty were formed. Conclusion: IVCM is a valuable tool for diagnosing filamentous fungal keratitis. In order to improve the reliability of IVCM, we suggest implementing a simple and clinically applicable grading system for aiding the interpretation of IVCM images of filamentous fungal keratitis.",
author = "Esben Nielsen and S Heegaard and Prause, {J U} and A Ivarsen and Mortensen, {K L} and J Hjortdal",
year = "2013",
month = "9",
doi = "10.1159/000357558",
language = "English",
volume = "4",
pages = "303--10",
journal = "Case Reports in Ophthalmology",
issn = "1663-2699",
publisher = "S. Karger AG",
number = "3",

}

RIS

TY - JOUR

T1 - Fungal keratitis - improving diagnostics by confocal microscopy

AU - Nielsen, Esben

AU - Heegaard, S

AU - Prause, J U

AU - Ivarsen, A

AU - Mortensen, K L

AU - Hjortdal, J

PY - 2013/9

Y1 - 2013/9

N2 - Purpose: Introducing a simple image grading system to support the interpretation of in vivo confocal microscopy (IVCM) images in filamentous fungal keratitis. Setting: Clinical and confocal studies took place at the Department of Ophthalmology, Aarhus University Hospital, Denmark. Histopathological analysis was performed at the Eye Pathology Institute, Department of Neuroscience and Pharmacology, University of Copenhagen, Denmark. Methods: A recent series of consecutive patients with filamentous fungal keratitis is presented to demonstrate the results from in-house IVCM. Based upon our experience with IVCM and previously published images, we composed a grading system for interpreting IVCM images of filamentous fungal keratitis. Results: A recent case series of filamentous fungal keratitis from 2011 to 2012 was examined. There were 3 male and 3 female patients. Mean age was 44.5 years (range 12-69), 6 out of 17 (35%) cultures were positive and a total of 6/7 (86%) IVCM scans were positive. Three different categories of IVCM results for the grading of diagnostic certainty were formed. Conclusion: IVCM is a valuable tool for diagnosing filamentous fungal keratitis. In order to improve the reliability of IVCM, we suggest implementing a simple and clinically applicable grading system for aiding the interpretation of IVCM images of filamentous fungal keratitis.

AB - Purpose: Introducing a simple image grading system to support the interpretation of in vivo confocal microscopy (IVCM) images in filamentous fungal keratitis. Setting: Clinical and confocal studies took place at the Department of Ophthalmology, Aarhus University Hospital, Denmark. Histopathological analysis was performed at the Eye Pathology Institute, Department of Neuroscience and Pharmacology, University of Copenhagen, Denmark. Methods: A recent series of consecutive patients with filamentous fungal keratitis is presented to demonstrate the results from in-house IVCM. Based upon our experience with IVCM and previously published images, we composed a grading system for interpreting IVCM images of filamentous fungal keratitis. Results: A recent case series of filamentous fungal keratitis from 2011 to 2012 was examined. There were 3 male and 3 female patients. Mean age was 44.5 years (range 12-69), 6 out of 17 (35%) cultures were positive and a total of 6/7 (86%) IVCM scans were positive. Three different categories of IVCM results for the grading of diagnostic certainty were formed. Conclusion: IVCM is a valuable tool for diagnosing filamentous fungal keratitis. In order to improve the reliability of IVCM, we suggest implementing a simple and clinically applicable grading system for aiding the interpretation of IVCM images of filamentous fungal keratitis.

U2 - 10.1159/000357558

DO - 10.1159/000357558

M3 - Journal article

VL - 4

SP - 303

EP - 310

JO - Case Reports in Ophthalmology

JF - Case Reports in Ophthalmology

SN - 1663-2699

IS - 3

ER -