Articulated vehicles composed of a tractor and a semi-trailer are dominant in international traffic within the EU. Also road trains can be obtained as an extended articulated vehicle by adding a trailer. A dolly carrying a semi-trailer may replace a road train in the same situation. The present paper investigates the dynamic amplification of a minor Danish highway bridge due to passage of such modular combination vehicle systems. A simulation model for a typical Danish highway bridge and the two different vehicles is established. The two different vehicles are a standard 48.8 ton articulated vehicle and a 60 ton vehicle consisting of a lorry and semi-trailer carried by a dolly. The dynamic parameters of the vehicles and the modal parameters of the bridge are estimated from measurements obtained for different passage situations of the two vehicles. Results show a good agreement between simulated and measured bridge acceleration response and dynamic amplification factors.