Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
Existing Data Sources in Clinical Epidemiology : The Danish COVID-19 Cohort. / Pottegård, Anton; Kristensen, Kasper Bruun; Reilev, Mette et al.
In: Clinical epidemiology, Vol. 12, No. 12, 2020, p. 875-881.Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review
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TY - JOUR
T1 - Existing Data Sources in Clinical Epidemiology
T2 - The Danish COVID-19 Cohort
AU - Pottegård, Anton
AU - Kristensen, Kasper Bruun
AU - Reilev, Mette
AU - Lund, Lars Christian
AU - Ernst, Martin Thomsen
AU - Hallas, Jesper
AU - Thomsen, Reimar Wernich
AU - Christiansen, Christian Fynbo
AU - Sørensen, Henrik Toft
AU - Johansen, Nanna Borup
AU - Støvring, Henrik
AU - Christensen, Steffen
AU - Kragh Thomsen, Marianne
AU - Husby, Anders
AU - Voldstedlund, Marianne
AU - Kjær, Jesper
AU - Brun, Nikolai C
N1 - © 2020 Pottegård et al.
PY - 2020
Y1 - 2020
N2 - Background: To facilitate research on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a prospective cohort of all Danish residents tested for SARS-CoV-2 in Denmark is established.Data Structure: All Danish residents tested by reverse transcriptase polymerase chain reactions (RT-PCR) for SARS-CoV-2 in Denmark are included. The cohort is identified using the Danish Microbiology Database. Individual-level record linkage between administrative and health-care registries is facilitated by the Danish Civil Registration System. Information on outcomes related to SARS-CoV-2 infection includes hospital admission, intensive care unit admission, mechanical ventilation, and death and is retrieved from the five administrative Danish regions, the Danish National Patient Registry, and the Danish Register of Causes of Death. The Patient Registry further provides a complete hospital contact history of somatic and psychiatric conditions and procedures. Data on all prescriptions filled at community pharmacies are available from the Danish National Prescription Registry. Health-care authorization status is obtained from the Danish Register of Healthcare Professionals. Finally, selected laboratory values are obtained from the Register of Laboratory Results for Research. The cohort is governed by a steering committee with representatives from the Danish Medicines Agency, Statens Serum Institut, the Danish Health Authority, the Danish Health Data Authority, Danish Patients, the Faculties of Health Sciences at the Danish universities, and Danish regions. The steering committee welcomes suggestions for research studies and collaborations. Research proposals will be prioritized based on timeliness and potential clinical and public health implications. All research protocols assessing specific hypotheses for medicines will be made publicly available using the European Union electronic Register of Post-Authorisation Studies.Conclusion: The Danish COVID-19 cohort includes all Danish residents with an RT-PCR test for SARS-CoV-2. Through individual-level linkage with existing Danish health and administrative registries, this is a valuable data source for epidemiological research on SARS-CoV-2.
AB - Background: To facilitate research on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a prospective cohort of all Danish residents tested for SARS-CoV-2 in Denmark is established.Data Structure: All Danish residents tested by reverse transcriptase polymerase chain reactions (RT-PCR) for SARS-CoV-2 in Denmark are included. The cohort is identified using the Danish Microbiology Database. Individual-level record linkage between administrative and health-care registries is facilitated by the Danish Civil Registration System. Information on outcomes related to SARS-CoV-2 infection includes hospital admission, intensive care unit admission, mechanical ventilation, and death and is retrieved from the five administrative Danish regions, the Danish National Patient Registry, and the Danish Register of Causes of Death. The Patient Registry further provides a complete hospital contact history of somatic and psychiatric conditions and procedures. Data on all prescriptions filled at community pharmacies are available from the Danish National Prescription Registry. Health-care authorization status is obtained from the Danish Register of Healthcare Professionals. Finally, selected laboratory values are obtained from the Register of Laboratory Results for Research. The cohort is governed by a steering committee with representatives from the Danish Medicines Agency, Statens Serum Institut, the Danish Health Authority, the Danish Health Data Authority, Danish Patients, the Faculties of Health Sciences at the Danish universities, and Danish regions. The steering committee welcomes suggestions for research studies and collaborations. Research proposals will be prioritized based on timeliness and potential clinical and public health implications. All research protocols assessing specific hypotheses for medicines will be made publicly available using the European Union electronic Register of Post-Authorisation Studies.Conclusion: The Danish COVID-19 cohort includes all Danish residents with an RT-PCR test for SARS-CoV-2. Through individual-level linkage with existing Danish health and administrative registries, this is a valuable data source for epidemiological research on SARS-CoV-2.
KW - Covid-19
KW - Database
KW - Epidemiology
KW - Follow-up
KW - Prognosis
KW - Prospective cohort
KW - SARS-CoV-2
KW - SYSTEM
KW - prognosis
KW - epidemiology
KW - follow-up
KW - database
KW - prospective cohort
KW - HEALTH
U2 - 10.2147/CLEP.S257519
DO - 10.2147/CLEP.S257519
M3 - Journal article
C2 - 32848476
VL - 12
SP - 875
EP - 881
JO - Clinical Epidemiology
JF - Clinical Epidemiology
SN - 1179-1349
IS - 12
ER -