Evolving complex insulation

Anastasia Liuzzi; Ditlev E Brodersen

doi:10.1038/s41589-021-00873-9

Evolving complex insulation

^*Corresponding author for this work

Department of Molecular Biology and Genetics - Protein Science

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Comment/debate/letter to the editor › Research › peer-review

Abstract

Prokaryotic genomes are rife with highly similar toxin-antitoxin modules that need to be protected and diversified at the same time. Studies of paralogous modules now reveal how evolution secures insulation between related systems, without compromising toxin inhibition.

Original language	English
Journal	Nature Chemical Biology
Volume	17
Issue	12
Pages (from-to)	1216-1217
Number of pages	2
ISSN	1552-4450
DOIs	https://doi.org/10.1038/s41589-021-00873-9
Publication status	Published - Dec 2021

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abstract = "Prokaryotic genomes are rife with highly similar toxin-antitoxin modules that need to be protected and diversified at the same time. Studies of paralogous modules now reveal how evolution secures insulation between related systems, without compromising toxin inhibition.",

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Evolving complex insulation

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