Enhanced automatic action imitation and intact imitation-inhibition in schizophrenia

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

DOI

Imitation plays a key role in social learning and in facilitating social interactions and likely constitutes a basic building block of social cognition that supports higher-level social abilities. Recent findings suggest that patients with schizophrenia have imitation impairments that could contribute to the social impairments associated with the disorder. However, extant studies have specifically assessed voluntary imitation or automatic imitation of emotional stimuli without controlling for potential confounders. The imitation impairments seen might therefore be secondary to other cognitive, motoric, or emotional deficits associated with the disorder. To overcome this issue, we used an automatic imitation paradigm with nonemotional stimuli to assess automatic imitation and the top-down modulation of imitation where participants were required to lift one of 2 fingers according to a number shown on the screen while observing the same or the other finger movement. In addition, we used a control task with a visual cue in place of a moving finger, to isolate the effect of observing finger movement from other visual cueing effects. Data from 33 patients (31 medicated) and 40 matched healthy controls were analyzed. Patients displayed enhanced imitation and intact top-down modulation of imitation. The enhanced imitation seen in patients may have been medication induced as larger effects were seen in patients receiving higher antipsychotic doses. In sum, we did not find an imitation impairment in schizophrenia. The results suggest that previous findings of impaired imitation in schizophrenia might have been due to other cognitive, motoric, and/or emotional deficits.

Original languageEnglish
JournalSchizophrenia Bulletin
Volume45
Issue1
Pages (from-to)87-95
Number of pages9
ISSN0586-7614
DOIs
Publication statusPublished - 2019

    Research areas

  • Antipsychotic medication, Mimicry, Social cognition, Social influence, Top-down control, FACIAL REACTIONS, MIMICRY, social cognition, BEHAVIOR, INTRANASAL OXYTOCIN, STIMULI, SOCIAL COGNITION, EXPRESSIONS, EMPATHY, top-down control, mimicry, GESTURE PERFORMANCE, DYSFUNCTION, social influence, antipsychotic medication, Humans, Middle Aged, Male, Antipsychotic Agents/therapeutic use, Adult, Female, Schizophrenia/drug therapy, Imitative Behavior/physiology, Inhibition (Psychology), Psychomotor Performance/physiology

See relations at Aarhus University Citationformats

ID: 121730079