Electrochemical immuno-and aptamer-based assays for bacteria: Pros and cons over traditional detection schemes

Rimsha Binte Jamal, Stepan Shipovskov, Elena E. Ferapontova*

*Corresponding author for this work

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

Abstract

Microbiological safety of the human environment and health needs advanced monitoring tools both for the specific detection of bacteria in complex biological matrices, often in the presence of excessive amounts of other bacterial species, and for bacteria quantification at a single cell level. Here, we discuss the existing electrochemical approaches for bacterial analysis that are based on the biospecific recognition of whole bacterial cells. Perspectives of such assays applications as emergency-use biosensors for quick analysis of trace levels of bacteria by minimally trained personnel are argued.

Original languageEnglish
Article number5561
JournalSensors (Switzerland)
Volume20
Issue19
Number of pages27
ISSN1424-8220
DOIs
Publication statusPublished - Oct 2020

Keywords

  • Bacteria
  • Electrochemical aptamer-based assays
  • Electrochemical ELISA
  • Electrochemical immunoassays
  • Electrochemistry

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