Electrochemical assays for microbial analysis: how far they are from solving microbiota and microbiome challenges

Elena E. Ferapontova

doi:10.1016/j.coelec.2019.12.005

Electrochemical assays for microbial analysis: how far they are from solving microbiota and microbiome challenges

Interdisciplinary Nanoscience Center

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21 Citations (Scopus)

Abstract

Bacterial sensors are indispensable in environmental monitoring, analysis of food and drink safety, prevention and treatment of pathogenic infections, antibiotic resistance screening, in combatting biocorrosion, and in biodefense. Recent discoveries within Human Microbiome project disclosed vital bacteria's role in human health and disease prognosis and treatment; they also placed in focus new analytical tools for bacterial analysis. Here, I discuss several basic concepts underlying the electrochemical bacterial biosensors: metabolic sensors, biosensors for DNA and RNA extracted from bacterial cells, and whole bacterial cell sensors, and their contribution to practically sought solutions for bacterial analysis. Current analytical issues and perspectives are outlined.

Original language	English
Journal	Current Opinion in Electrochemistry
Volume	19
Pages (from-to)	153-161
Number of pages	9
ISSN	2451-9103
DOIs	https://doi.org/10.1016/j.coelec.2019.12.005
Publication status	Published - 2020

Keywords

Bacterial sensors
Electrochemical ELISA
Electrochemical sensors
Metabolic biosensors
Pathogen analysis
Whole-cell analysis

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10.1016/j.coelec.2019.12.005

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title = "Electrochemical assays for microbial analysis: how far they are from solving microbiota and microbiome challenges",

abstract = "Bacterial sensors are indispensable in environmental monitoring, analysis of food and drink safety, prevention and treatment of pathogenic infections, antibiotic resistance screening, in combatting biocorrosion, and in biodefense. Recent discoveries within Human Microbiome project disclosed vital bacteria's role in human health and disease prognosis and treatment; they also placed in focus new analytical tools for bacterial analysis. Here, I discuss several basic concepts underlying the electrochemical bacterial biosensors: metabolic sensors, biosensors for DNA and RNA extracted from bacterial cells, and whole bacterial cell sensors, and their contribution to practically sought solutions for bacterial analysis. Current analytical issues and perspectives are outlined.",

keywords = "Bacterial sensors, Electrochemical ELISA, Electrochemical sensors, Metabolic biosensors, Pathogen analysis, Whole-cell analysis",

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T2 - how far they are from solving microbiota and microbiome challenges

AU - Ferapontova, Elena E.

PY - 2020

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N2 - Bacterial sensors are indispensable in environmental monitoring, analysis of food and drink safety, prevention and treatment of pathogenic infections, antibiotic resistance screening, in combatting biocorrosion, and in biodefense. Recent discoveries within Human Microbiome project disclosed vital bacteria's role in human health and disease prognosis and treatment; they also placed in focus new analytical tools for bacterial analysis. Here, I discuss several basic concepts underlying the electrochemical bacterial biosensors: metabolic sensors, biosensors for DNA and RNA extracted from bacterial cells, and whole bacterial cell sensors, and their contribution to practically sought solutions for bacterial analysis. Current analytical issues and perspectives are outlined.

AB - Bacterial sensors are indispensable in environmental monitoring, analysis of food and drink safety, prevention and treatment of pathogenic infections, antibiotic resistance screening, in combatting biocorrosion, and in biodefense. Recent discoveries within Human Microbiome project disclosed vital bacteria's role in human health and disease prognosis and treatment; they also placed in focus new analytical tools for bacterial analysis. Here, I discuss several basic concepts underlying the electrochemical bacterial biosensors: metabolic sensors, biosensors for DNA and RNA extracted from bacterial cells, and whole bacterial cell sensors, and their contribution to practically sought solutions for bacterial analysis. Current analytical issues and perspectives are outlined.

KW - Bacterial sensors

KW - Electrochemical ELISA

KW - Electrochemical sensors

KW - Metabolic biosensors

KW - Pathogen analysis

KW - Whole-cell analysis

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DO - 10.1016/j.coelec.2019.12.005

M3 - Review

AN - SCOPUS:85078722218

SN - 2451-9103

VL - 19

SP - 153

EP - 161

JO - Current Opinion in Electrochemistry

JF - Current Opinion in Electrochemistry

ER -

Electrochemical assays for microbial analysis: how far they are from solving microbiota and microbiome challenges

Abstract

Keywords

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