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Electrochemical assays for microbial analysis: how far they are from solving microbiota and microbiome challenges

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Bacterial sensors are indispensable in environmental monitoring, analysis of food and drink safety, prevention and treatment of pathogenic infections, antibiotic resistance screening, in combatting biocorrosion, and in biodefense. Recent discoveries within Human Microbiome project disclosed vital bacteria's role in human health and disease prognosis and treatment; they also placed in focus new analytical tools for bacterial analysis. Here, I discuss several basic concepts underlying the electrochemical bacterial biosensors: metabolic sensors, biosensors for DNA and RNA extracted from bacterial cells, and whole bacterial cell sensors, and their contribution to practically sought solutions for bacterial analysis. Current analytical issues and perspectives are outlined.

Original languageEnglish
JournalCurrent Opinion in Electrochemistry
Volume19
Pages (from-to)153-161
Number of pages9
ISSN2451-9103
DOIs
Publication statusPublished - 2020

    Research areas

  • Bacterial sensors, Electrochemical ELISA, Electrochemical sensors, Metabolic biosensors, Pathogen analysis, Whole-cell analysis

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