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Efficient Knockdown and Lack of Passenger Strand Activity by Dicer-Independent shRNAs Expressed from Pol II-Driven MicroRNA Scaffolds

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Efficient Knockdown and Lack of Passenger Strand Activity by Dicer-Independent shRNAs Expressed from Pol II-Driven MicroRNA Scaffolds. / Kaadt, Erik; Alsing, Sidsel; Cecchi, Claudia R.; Damgaard, Christian Kroun; Corydon, Thomas J.; Aagaard, Lars.

In: Molecular Therapy - Nucleic Acids, Vol. 14, 01.03.2019, p. 318-328.

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

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@article{e4ae4aa84d5a46b2a3cf5de53b7b176c,
title = "Efficient Knockdown and Lack of Passenger Strand Activity by Dicer-Independent shRNAs Expressed from Pol II-Driven MicroRNA Scaffolds",
keywords = "agoshRNA, agshRNA, Dicer-independent shRNA, Drosha, miR-324, miR-451, passenger strand activity, Pol-II driven miRNA scaffold, RNAi, U1 promoter",
author = "Erik Kaadt and Sidsel Alsing and Cecchi, {Claudia R.} and Damgaard, {Christian Kroun} and Corydon, {Thomas J.} and Lars Aagaard",
year = "2019",
month = "3",
day = "1",
doi = "10.1016/j.omtn.2018.11.013",
language = "English",
volume = "14",
pages = "318--328",
journal = "Molecular Therapy - Nucleic Acids",
issn = "2162-2531",
publisher = "Nature Publishing Group",

}

RIS

TY - JOUR

T1 - Efficient Knockdown and Lack of Passenger Strand Activity by Dicer-Independent shRNAs Expressed from Pol II-Driven MicroRNA Scaffolds

AU - Kaadt, Erik

AU - Alsing, Sidsel

AU - Cecchi, Claudia R.

AU - Damgaard, Christian Kroun

AU - Corydon, Thomas J.

AU - Aagaard, Lars

PY - 2019/3/1

Y1 - 2019/3/1

KW - agoshRNA

KW - agshRNA

KW - Dicer-independent shRNA

KW - Drosha

KW - miR-324

KW - miR-451

KW - passenger strand activity

KW - Pol-II driven miRNA scaffold

KW - RNAi

KW - U1 promoter

UR - http://www.scopus.com/inward/record.url?scp=85059868564&partnerID=8YFLogxK

U2 - 10.1016/j.omtn.2018.11.013

DO - 10.1016/j.omtn.2018.11.013

M3 - Journal article

VL - 14

SP - 318

EP - 328

JO - Molecular Therapy - Nucleic Acids

JF - Molecular Therapy - Nucleic Acids

SN - 2162-2531

ER -