DNA Electrochemistry and Electrochemical Sensors for Nucleic Acids

Elena E. Ferapontova*

*Corresponding author for this work

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperReviewResearchpeer-review

1 Citation (Scopus)

Abstract

Sensitive, specific, and fast analysis of nucleic acids (NAs) is strongly needed in medicine, environmental science, biodefence, and agriculture for the study of bacterial contamination of food and beverages and genetically modified organisms. Electrochemistry offers accurate, simple, inexpensive, and robust tools for the development of such analytical platforms that can successfully compete with other approaches for NA detection. Here, electrode reactions of DNA, basic principles of electrochemical NA analysis, and their relevance for practical applications are reviewed and critically discussed.

Original languageEnglish
JournalAnnual Review of Analytical Chemistry
Volume11
Pages (from-to)197-218
Number of pages22
ISSN1936-1327
DOIs
Publication statusPublished - 12 Jun 2018

Keywords

  • DNA-mediated electron transfer
  • electrocatalytic sensors
  • electrochemical beacons
  • electrochemical DNA biosensors
  • hybridization
  • redox indicators

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