Difficult to control atopic dermatitis

Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaperJournal articleResearchpeer-review

  • Ulf Darsow
  • ,
  • Andreas Wollenberg
  • ,
  • Dagmar Simon
  • ,
  • Alain Taïeb
  • ,
  • Thomas Werfel
  • ,
  • Arnold Oranje
  • ,
  • Carlo Gelmetti
  • ,
  • Ake Svensson
  • ,
  • Mette Deleuran
  • Anne-Marie Calza
  • ,
  • Francesca Giusti
  • ,
  • Jann Lübbe
  • ,
  • Stefania Seidenari
  • ,
  • Johannes Ring
  • ,
  • European Task Force on Atopic Dermatitis / EADV Eczema Task Force
Difficult to control atopic dermatitis (AD) presents a therapeutic challenge and often requires combinations of topical and systemic treatment. Anti-inflammatory treatment of severe AD most commonly includes topical glucocorticosteroids and topical calcineurin antagonists used for exacerbation management and more recently for proactive therapy in selected cases. Topical corticosteroids remain the mainstay of therapy, the topical calcineurin inhibitors tacrolimus and pimecrolimus are preferred in certain locations. Systemic anti-inflammatory treatment is an option for severe refractory cases. Microbial colonization and superinfection contribute to disease exacerbation and thus justify additional antimicrobial / antiseptic treatment. Systemic antihistamines (H1) may relieve pruritus but do not have sufficient effect on eczema. Adjuvant therapy includes UV irradiation preferably of UVA1 wavelength. "Eczema school" educational programs have been proven to be helpful.
Original languageEnglish
JournalThe World Allergy Organization Journal
Volume6
Issue1
Pages (from-to)6
ISSN1939-4551
DOIs
Publication statusPublished - 2013

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