Design of an early intervention for persistent post-concussion symptoms in adolescents and young adults: A feasibility study

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BACKGROUND: About 5-15 % of patients with concussion experience persistent post-concussion symptoms (PCS) longer than 3 months post-injury.

OBJECTIVE: To explore the feasibility of a new intervention for young patients with persistent PCS and long-term changes after intervention.

METHODS: Thirty-two consecutive patients (15-30 years) with persistent PCS 2-4 months post-injury were recruited from a cohort study or referred to a non-randomized feasibility study of an individually tailored, 8-week, multidisciplinary intervention. Assessment was performed at baseline, end of intervention (EOI), and at 3- and 12-month follow-up (FU). Main measures were The Experience of Service Questionnaire (ESQ), Rivermead Post-Concussion Symptoms Questionnaire (RPQ) and The Quality of Life after Brain Injury - Overall Scale (QOLIBRI-OS).

RESULTS: Twenty-three (72%) patients completed the intervention. The ESQ demonstrated high patient satisfaction. There was a decrease of PCS and an increase in quality of life from baseline to EOI: RPQ score -8.9 points, 95% CI 4.5 to 13.3, p < 0.001; QOLIBRI-OS score +10.5 points, 95% CI 2.5 to 18.5, p = 0.010. Improvement was maintained at 3- and 12-month FU.

CONCLUSION: The new early intervention is feasible and may prevent chronification of PCS. An RCT is currently performed to evaluate the effect of the intervention.

Original languageEnglish
JournalNeuroRehabilitation
Volume43
Issue2
Pages (from-to)155-167
Number of pages13
ISSN1053-8135
DOIs
Publication statusPublished - 2018

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