Dapsoninduceret fald i HbA1c kan give et falskt billede af diabeteskontrollen

Translated title of the contribution: Dapsone-induced decrease in the HbA(1c) level may cause artefacts in diabetic control

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Abstract

Glycated haemoglobin (HbA(1c)) level is used to monitor glycaemic control in diabetic patients, and has recently been included as a diagnostic factor for type 2 diabetes mellitus (DM). A 50-year-old male with well-controlled type 1 DM, Mb Addison and coeliac disease was diagnosed with dermatitis herpetiformis and treated with dapsone. Subsequently, the patient presented a pronounced drop in HbA(1c) levels without changes in blood glucose levels. S-fructosamine values were in agreement with the previous stable HbA(1c) values. Blood analyses showed inappropriately low HbA(1c) values due to mild haemolysis and shortening of erythrocyte lifetime without anaemia.
Translated title of the contributionDapsone-induced decrease in the HbA(1c) level may cause artefacts in diabetic control
Original languageDanish
JournalUgeskrift for Læger
Volume175
Issue8
Pages (from-to)505-6
Number of pages2
ISSN0041-5782
Publication statusPublished - 18 Feb 2013

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